Charles Laurito, M.D.
Professor, Anesthesiology, Anatomy & Cell Biology
Disease/Therapeutics, Cellular/Molecular
How noxious stimuli are perceived as being painful: specifically what neurotransmitters are released at the spinal cord level. Can pain relief be provided by blocking these molecules?
Selected references
- Park TJ, Lu Y, Juttner R, Smith ESJ, Hu J, Brand A, Wetzel C, Milenkovic N, Erdmann B, Heppenstall, PA, Laurito CE, Wilson SP, Lewin GR. Selectivity inflammatory pain insensitivity in the African naked mole-rat (Heterocephalus glaber). PLoS Biol 6(1):e13 doi:10.1371/jounral.pbio.0060013.
- Tzabazis AZ, Pirc G, Votta-Velis EG, Wilson SP, Laurito CE, and Yeomans DC. Antihyperalgesic effect of a recombinant herpes virus encoding antisense for calcitonin gene related peptide. Anesthiol. 2007:1196-1203.
- Yeomans CD, Lu Y, Laurito CE, Votta-Velis EG, Wilson SP, and Pappas GD. Recombinant herpes vector-mediated analgesia in a primate model of hyperalgesia. Molec. Ther. 2006 March, 13(3):589-598.