Gustavo Pigino, Ph.D.
Research Assistant Professor, Anatomy & Cell Biology

pigino@uic.edu

Cellular/Molecular, Disease/Therapeutics
Alzheimer’s disease, Huntington’s disease, Parkinson’s disease, molecular mechanisms of neurodegeneration, axonal transport and aging.

Selected references

• DeBoer SR, You Y, Szodorai A, Kaminska A, Pigino G, Nwabuisi E, Wang B, Estrada-Hernandez T, Kins S, Brady ST, Morfini G. Conventional kinesin holoenzymes are composed of heavy and light chain homodimers.
  Biochemistry. 2008 Apr 15;47(15):4535-43.
• Morfini G, Pigino G, Brady ST. Approaches to kinesin-1 phosphorylation. Methods Mol Biol. 2007;392:51-69.
• Lazarov O, Morfini GA, Pigino G, Gadadhar A, Chen X, Robinson J, Ho H, Brady ST, Sisodia SS. Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer's disease-linked mutant presenilin 1. J Neurosci. 2007;27(26):7011-20.