Neelima Chauhan, Ph.D.
Research Assistant Professor, Anatomy & Cell Biology
Disease/Therapeutics, Cognition/Learning
Preventing and reversing Alzheimer’s disease (AD) pathogenesis and promoting repair of degenerated neurons in Traumatic Brain Injury (TBI) by testing candidate therapies on pre-clinical basis, including intracerebroventricular passive immunization, antisense strategies, phosphodiesterase inhibitors, statins, lithium, and aged garlic extract.
Selected references
- Chauhan NB, Sandoval J. Amelioration of early cognitive deficits by aged garlic extract in Alzheimer's transgenic mice. Phytother Res. 2007 Jul;21(7):629-40.
- Chauhan NB, Siegel GJ. Antisense inhibition at the beta-secretase-site of beta-amyloid precursor protein reduces cerebral amyloid and acetyl cholinesterase activity in Tg2576. Neuroscience. 2007 Apr 25;146(1):143-51.
- Chauhan NB. Intracerebroventricular passive immunization with anti-oligoAbeta antibody in TgCRND8 J Neurosci Res. 2007 Feb 1;85(2):451-63.