Alessandro Guidotti, M .D.
Professor of Biochemistry, Psychiatry
Epigenetic mechanisms in schizophrenia. Neurosteroids and depression. Second generation benzodiazepine pharmacology.
- Costa E, Dong E, Grayson DR, Guidotti A, Ruzicka WB, Veldic M. Reviewing the role of DNA (cytosine-5) methyltransferase overexpression in the cortical GABAergic dysfunction associated with psychosis vulnerability. Epigenetics, 2007; 2:29-36.
- Pibiri F, Nelson M, Guidotti A, Costa E, Pinna G. Downregulation of allopregnanolone brain expression during social isolation enhances contextual fear: a model relevant for posttraumatic stress disorder (PTSD). PNAS, 2008; 105, 5567-5572..
- Dong E, Nelson M, Grayson DR, Costa E, Guidotti A. Clozapine and sulpiride but not haloperidol or olanzapine activate nuclear DNA-demethylation in the brain. PNAS, 2008; September.