Susan W. Liebman, Ph.D.
Distinguished Professor, Biological Sciences
Cellular/Molecular
We study yeast prions and use yeast as a model to study protein misfolding diseases including Alzheimer's disease.
Selected references
- Bagriantsev SN, Gracheva EO, Richmond JE, Liebman SW.Variant-specific [PSI+] Infection Is Transmitted by Sup35 Polymers within [PSI+] Aggregates with Heterogeneous Protein Composition. Mol Biol Cell. 2008 Jun;19(6):2433-43.
- Taneja V, Maddelein ML, Talarek N, Saupe SJ, Liebman SW.A non-Q/N-rich prion domain of a foreign prion, [Het-s], can propagate as a prion in yeast. Mol Cell. 2007 Jul 6;27(1):67-77.
- Bagriantsev S, Liebman S.Modulation of Abeta42 low-n oligomerization using a novel yeast reporter system. BMC Biol. 2006 Sep 26;4:32.