Yasuko Nakajima, M.D., Ph.D.
Professor, Anatomy & Cell Biology
Cellular/Molecular, Disease/Therapeutics
Studies of ion channels and signal transduction in brain neurons related to sleep disorders and Alzheimer’s disease, obesity and mental disorders.
Selected references
- Kawano T, Zhao P, Floreani CV, Nakajima Y, Kozasa T, Nakajima S. Interaction of Gq and Kir3 (GIRK) channels. Mol. Pharmacol. 2007 Apr; 71: 1179-1184.
- Yasufuku-Takano J, Nakajima S, Nakajima, Y. (2008) Morphological and physiological properties of serotonergic neurons in dissociated cultures from the postnatal rat dorsal raphe nucleus. J. Neuroscience Methods, 2008 Jan 30;167:258-267.
- Imanishi M, Nakajima Y, Tomishima Y, Hamashima H, Washizuka K, Sakurai M, Matsui S, Imamura E, Ueshima K, Yamamoto T, Yamamoto N, Ishikawa H, Nakano K, Unami N, Hamada K, Matsumura Y, Takamura F, Hattori K. Discovery of a novel series of benzoic acid derivatives as potent and selective human beta3 adrenergic receptor agonists with good oral bioavailability. 3. Phenylethanolaminotetraline (PEAT) skeleton containing biphenyl or biphenyl ether moiety. J Med Chem. 2008 Aug 14;51(15):4804-22. Epub 2008 Jul 24.