Z. Jim Wang, Ph.D.
Associate Professor, Chemistry, Bioengineering
Cellular/Molecular, Disease/Therapeutics
Our research concentrates on understanding mechanisms of chronic pain and drug addiction; as well as developing new pharmacological treatments for these conditions. We apply the power of neurobiology, molecular pharmacology, molecular genetics and bioinformatics, and targeted delivery.
Selected references
- Wang LX and Wang ZJ. Animal and cellular models of chronic pain. sh-pull perfusion. Advanced Drug Delivery Reviews. 2003;55:949-965. Available here.
- Wang ZJ and Wang LX. Phsphorylation: A molecular switch in opiod tolerance. Life Sciences. 2006;79:1681-1691. Available here.
- He Y, Yang C, Kirkmire CM, Wang ZJ. Regulation of Opioid Tolerance by let-7 Family MicroRNA Targeting the μ Opioid Receptor. J of Neurosci 2010 Jul 28; 30(30):10251-10258. Available here.