Centre for Addiction and Mental Health, University of Toronto. The Centre for Addiction and Mental Health (CAMH) is Canada's leading addiction and mental health teaching hospital. CAMH succeeds in transforming the lives of people affected by addiction and mental illness, by applying the latest in scientific advances, through integrated and compassionate clinical practice, health promotion, education and research.

Center for Substance Abuse Research (CESAR), at the University of Maryland at College Park. The mission of CESAR is to inform policymakers, practitioners, and the general public about substance abuse—its nature and extent, its prevention and treatment, and its relation to other problems. In pursuing its mission, CESAR conducts policy-relevant research and evaluation studies, disseminates statistical and other information, assists in training students in substance abuse research methods and policy analysis, and provides technical assistance to agencies and organizations working in substance abuse related fields.

Criminal Justice Drug Abuse Treatment Studies (CJ-DATS) Centers. The National Institute on Drug Abuse (NIDA) established CJ-DATS as a cooperative research program to explore the issues related to the complex system of offender treatment services. Nine research centers and a Coordinating Center were created in partnership with researchers, criminal justice professionals, and drug abuse treatment practitioners to form a national research infrastructure.

	Center for the Integration of Substance Abuse Research and Practice, National Development and Research Institute, Inc. (NDRI), New York, New York (Region: Rocky Mountains). Harry K. Wexler is the principal investigator.
	UCLA Integrated Substance Abuse Program, Los Angeles, California (Region: Pacific Coast). Michael L. Prendergast is the principal investigator.
	Center for Drug and Alcohol Studies, University of Delaware (Region: Mid-Atlantic). James A. Inciardi is the principal investigator.
	Center for Treatment Research on Adolescent Substance Abuse, Miami University School of Medicine (Region: Florida), Howard Liddle is the principal investigator.
	Connecticut Department of Mental Health and Addiction Services (Region: Connecticut). Linda K. Frisman is the principal investigator.
	Substance Abuse Research Unit, Lifespan Hospitals, Providence, Rhode Island (Region: Rhode Island). Peter D. Friedmann is the principal investigator.
	Institute of Behavioral Research, Texas Christian University, Fort Worth, Texas (Region: Southwest). D. Dwayne Simpson is the principal investigator.
	Center on Drug and Alcohol Research, University of Kentucky, Lexington (Region: Central States). Carl G. Leukefeld is the principal investigator.
	Virginia Commonwealth University, Virginia (Coordinating Center), Faye Taxman is the principal investigator.

Criminal Justice Mental Health Consensus Project is a national effort coordinated by the Council of State Governments (CSG) to help local, state, and federal policymakers and criminal justice and mental health professionals improve the response to people with mental illness who become involved in, or are at risk of involvement in, the criminal justice system.

GAINS Center - The GAINS Center's primary focus is on expanding access to community based services for adult's diagnosed with co-occurring mental illness and substance use disorders at all points of contact with the justice system. The Center emphasizes the provision of consultation and technical assistance to help communities achieve integrated systems of mental health and substance abuse services for individuals in contact with the justice system.

National Center on Addiction and Substance Abuse (CASA) at Columbia University. The mission of CASA is to inform Americans of the economic and social costs of substance abuse and its impact on their lives; assess what works in prevention, treatment, and law enforcement; encourage every individual and institution to take responsibility to combat substance abuse and addiction; provide those on the front lines with the tools they need to succeed; and remove the stigma of abuse and replace shame and despair with hope.

National Drug Abuse Treatment Clinical Trials Network - To date, the efficacy of new treatments for drug addiction has been demonstrated primarily in specialized research settings, with somewhat restricted patient populations. To address this problem, the National Institute on Drug Abuse (NIDA) has established the National Drug Abuse Treatment Clinical Trials Network (CTN). The mission of the CTN is twofold: Conduct studies of behavioral, pharmacological, and integrated behavioral and pharmacological treatment interventions of therapeutic effect in rigorous, multisite clinical trials to determine effectiveness across a broad range of community-based treatment settings and diversified patient populations; and transfer the research results to physicians, providers, and their patients to improve the quality of drug abuse treatment throughout the country using science as the vehicle.