Department of Biopharmaceutical Sciences

College of Pharmacy
masthead

Richard A. Gemeinhart, Ph.D.

Richard A. Gemeinhart, Ph.D.

Associate Professor of Pharmaceutics and Bioengineering

Contact Information
833 South Wood Street
357 PHARM, MC 865
Chicago, IL 60612-7231
Office: (312) 996-2253
Fax: (312) 996-0098
Email: rag@uic.edu
Lab Website

Education


Postdoctoral - Cornell University - 2001
Ph.D. - Purdue University - 1999
B.S.E. - Purdue University - 1994


Research Interests
(Hide All or Show All Publications)

Tissue Regeneration
Micro/Nanostructures
Therapeutic Drug Conjugates
Other Research

Publications (2009-2014) Pubmed Citations
Rayahin JE, Buhrman JS, Gemeinhart RA. Melittin, as a glutathione S-transferase fusion protein, maintains anti-inflammatory properties while diminishing toxicity, European Journal of Pharmaceutical Sciences, In press. DOI
Zhang Y, Köllmer M, Buhrman JS, Tang MY, Gemeinhart RA. Arginine-rich, Cell Penetrating Peptide-microRNA Inhibitor Complexes Decrease Glioblastoma Migration Potential. Peptides. 2014; 58(1): 83-90. DOI
Zellander A, Zhao H, Kotecha M, Low, K-B, Gemeinhart RA, Wardlow M, Abiade J, Cho M. Characterization of Pore Structure in Biologically Functional Poly(2-Hydroxyethyl Methacrylate) - Poly(Ethylene Glycol) Diacrylate (PHEMA-PEGDA), PLOS One. 2014; 9(5): e96709. DOI
Sharma V, Köllmer M, Szymusiak M, Nitsche LC, Gemeinhart RA, Liu Y. Toroidal-spiral particles for co-delivery of anti-VEGFR-2 antibody and irinotecan – a potential implant to hinder recurrence of glioblastoma multiforme, Biomacromolecules. 2014; 15(3): 756-762. DOI
Zhang H, Wang X, Dai W, Gemeinhart RA, Zhang Q, Li T. Pharmacokinetics and Treatment Efficacy of Camptothecin Nanocrystals on Lung Metastasis. Molecular Pharmaceutics. 2013; 11(1): 226-233. DOI
Zhang Y, Wang ZJ, and Gemeinhart RA. Progress in microRNA Delivery. Journal of Controlled Release. 2013; 172(3): 962-974. DOI
Buhrman JS, Cook LC, Rayahin, JE, Federle MJ, Gemeinhart RA. Soluble recombinant melittin purified by extracting insoluble lysate of Escharia coli without denaturation is as functional as chemically synthesized melittin. Biotechnology Progress. 2013; 29(5): 1150-1157. DOI
Köllmer M, Popescu C, Manda P, Zhou L, Gemeinhart RA. Stability of Benzocaine Formulated in Commercial Oral Disintegrating Tablet Platforms. AAPS PharmSciTec. 2013 14(4):1333-1340. DOI
Hollis CP, Weiss HL, Leggas M, Evers BM, Gemeinhart RA, Li T. Biodistribution and Bioimaging Studies of Hybrid Paclitaxel Nanocrystals: Lessons Learned of the EPR Effect and Image-Guided Drug Delivery. Journal of Controlled Release. 2013; 172(1): 12-21. DOI
Buhrman JS, Cook LC, Rayahin, JE, Federle MJ, Gemeinhart RA. Proteolytically activated anti-bacterial hydrogel microspheres. Journal of Controlled Release. 2013; 171(3): 288-295. DOI
Köllmer M, Buhrman JS, Zhang Y, Gemeinhart RA. Markers Are Shared Between Adipogenic and Osteogenic Differentiated Mesenchymal Stem Cells. Journal of Developmental Biology and Tissue Engineering. 2013; 5(2): 18-25. DOI
Zellander A, Gemeinhart RA, Djalilian AR, Makhsous M, Sun S, Cho MR. Desiging a Gas Foamed Scaffold for Keratoprosthesis. Material Science and Engineering C-Materials for Biological Applications. 2013; 33(6): 3396-3403. DOI
Hollis CP, Weiss HL, Evers BM, Gemeinhart RA, Li T. In Vivo Investigation of Hybrid Paclitaxel Nanocrystals with Dual Fluorescent Probes for Cancer Theranostics, Pharmaceutical Research. 2014: 31(6): 1450-1459. DOI
Buhrman JS, Rayahin JE, Köllmer M, Gemeinhart RA. In-house preparation of hydrogels for batch affinity purification of glutathione S-transferase tagged recombinant proteins, BMC Biotechnology, 2012; 12(1): 63. DOI
Köllmer M, Keskar V, Hauk TG, Collins JM, Russell B, Gemeinhart RA. Stem Cell-derived Extracellular Matrix Enables Survival and Multi-Lineage Differentiation within Superporous Hydrogels. Biomacromolecules. 2012; 13(4): 963-973. DOI
Zhang Y, Gemeinhart RA. Improving Matrix Metalloproteinase-2 Specific Response of a Hydrogel System using Electrophoresis. International Journal of Pharmaceutics. 2012; 429(1-2): 31-37. DOI
Rayahin JE, Buhrman JS, Gemeinhart RA. Hybrid Nanocrystals: University of Kentucky US 2006/0280680A1. Expert Opin. Ther. Patents. 2012; 22(3): 341-348. DOI
Desai ES, Tang MY, Ross, A, Gemeinhart RA. Macroporous Hydrogel Scaffolds: A Platform for Cell Encapsulation. Biomedical Materials. 2012; 7(2): 024108. DOI
Shafiq MA, Gemeinhart RA, Yue BY, and Djalilian AR. Decellularized Human Cornea for Reconstructing the Corneal Epithelium and Anterior Stroma. Tissue Engineering, Part C-Methods. 2012; 18(5): 340-348. DOI
Zhao RS, Hollis CP, Zhang H, Sun L, Gemeinhart RA, and Li T. Hybrid Nanocrystals: Achieving Concurrent Therapeutic and Bioimaging Functionalities Toward Solid Tumors. Mol. Pharmaceutics. 2011; 8(5): 1985-1991. DOI
Gemeinhart RA, Tauro JR. Composition and Method for Providing Localized Delivery of a Therapeutic Agent. US 7,943,569 (May 17, 2011).
Bae M, Divan R, Suthar KJ, Mancini DC, Gemeinhart RA. Fabrication of PEG Hydrogel Particles for Pharmaceutics using Electron beam and Optical Lithography, Journal of Vaccuum Science and Technology-B. 2010; 28(6): C6P24-C6P26.
Vartak DG, Lee BS, Gemeinhart RA. In vitro evaluation of functional interaction of integrin avß3 and matrix metalloprotease-2. Mol. Pharmaceutics. 2009; 6(6): 1856-1867.DOI
Keskar V, Gandhi M, Gemeinhart EJ, Gemeinhart RA. Initial Evaluation of Vascular Ingrowth into Superporous Hydrogels. J. Tissue Eng. Regen. Med. 2009; 3(6): 486-490. DOI
Gandhi M, Srikar R, Yarin AL, Megaridis CM, Gemeinhart RA. Mechanistic Examination of Protein Release from Polymer Nanofibers. Mol. Pharmaceutics. 2009; 6(2): 641-647. DOI
Keskar V, Marion NW, Mao JJ, Gemeinhart RA. In Vitro Evaluation of Macroporous Hydrogels to Facilitate Stem Cell Infiltration, Growth and Mineralization. Tissue Eng. 2009; 15A(7): 1695-1707. DOI