The Hong Research Group is located in the Department of Biopharmaceutical Sciences at University of Illinois at Chicago. The newly-renovated first-class laboratory is located within the UIC college of pharmacy that is in the heart of the Illinois Medical District, which includes the University of Illinois Medical Center, Rush University Hospitals, and other health science colleges and hospitals.


Our research focus lies at the interface of materials science, biology and nanotechnology to develop novel polymeric nanodevices for biological analysis, diagnostics and therapeutics. The ultimate goal of our laboratory is to achieve marriage of biomimetics and nanotechnology. Our work is being conducted in a highly interdisciplinary and collaborative environment that provides opportunities for students with backgrounds and/or interests in chemistry, engineering, biology, medicine and pharmaceutical sciences.

More specifically, we are interested in understanding and controlling biological interactions of polymers with cells at the nano-scale. The fundamental understanding will lead us to more translational cancer research fields including: i) Targeted drug delivery with enhanced targeting efficacy using newly designed nanocarriers; ii) Local, transdermal delivery of drugs such as chemo-preventive medicine; and iii) Biomimetic multifunctional devices for effective detection and isolation of rare cells such as circulating tumor cells (CTCs).

Hong Lab 2013

From left to right, Seungpyo Hong, Ashley Cha, Jason Bugno, Suhair Sunoqrot, Ryan Pearson, Yang Yang, Kevin Tam, Jeeho Lee, Hao-jui Hsu, Frehiwot Gebrehiwot, Matthew Pasco, Ja Hye Myung

Missing members: Marilyn Gaske



A 2006 paper that Dr. Hong first authored is selected as one of the top 25 articlesin the first 25 years of Biooconjugate Chemistry! http://pubs.acs.org/page/bcches/thematic/25th-anniversary.html


Dr. Hong visits the University of Nebraska Medical Center's NanoMedicine Center, delivering a center seminar on our reserch topics: Drug Delivery and Tumor Cell capturing using dendritic nanomaterials.


Dr. Hong visits India, joining two conferences in New Delhi and Chandigargh. He is one of the invited speakers for the Indo-US NanoEngineering Workshop held at AIIMS in New Dehli and the NanoScience and Engineering Conference held in Chandigargh. He also participates in a forum discussing future directions of the research strategy with Dr. K. VijayRaghavan, the Secretary of Department of Biotechnology of Indian Government.


Dr. Hong visits Korea and China, giving in total of 8 invited talks at IBEC 2014, Chunnam National University, Yonsei University, Korea University of Science and Technology, KAIST, KIST, Donghua University, and Amway China.


Dr. Hong joins N.I.C.E. Meeting held in Nice, France to give a talk related to our biomimetic approaches for effective capture and isolation of circulating tumor cells.


Dr. Hong visits the University of North Carolina at Chapel Hill to give a seminar in the Radiation Oncology Department.


Our paper entitled "Poly(ethylene glycol) Corona Chain Length Controls End-Group-Dependent Cell Interactions of Dendron Micelles" is accepted for publication in Macromolecules! The authors are the first author Hao-jui, Soumyo, Ryan, Sayam, Dr. Kral, and Dr. Hong. This is the 50th paper published by Dr. Hong. Congratulations!


Ryan successfully defends his PhD disseration, becoming the 4th PhD from the group. Congratulations, Dr. Pearson!!!


Dr. Hong promotes to Associate Professor with Indefinite Tenure. He is also appointed as Director of Graduate Eduation for the College of Pharmacy. Congratulations!


NSF supports our hybrid nanoparticle project for next three years!


Dr. Hong delivers a featured invited talk at The 46th Pharmaceutics Graduate Student Research Meeting (PGSRM) held in Chicago hosted by UIC College of Pharmacy.


Dr. Hong Y. Cho from Carnegie Mellon University joins our lab as a Postdoctoral Associate He recently finished his PhD working with Prof. Krzysztof Matyjaszewski in the Chemistry Department of CMU. Welcome Dr. Cho!