The Hong Research Group is located in the Department of Biopharmaceutical Sciences at University of Illinois at Chicago. The newly-renovated first-class laboratory is located within the UIC college of pharmacy that is in the heart of the Illinois Medical District, which includes the University of Illinois Medical Center, Rush University Hospitals, and other health science colleges and hospitals.
WHAT WE DO?
Our research focus lies at the interface of materials science, biology and nanotechnology to develop novel polymeric nanodevices for biological analysis, diagnostics and therapeutics. The ultimate goal of our laboratory is to achieve marriage of biomimetics and nanotechnology. Our work is being conducted in a highly interdisciplinary and collaborative environment that provides opportunities for students with backgrounds and/or interests in chemistry, engineering, biology, medicine and pharmaceutical sciences.
More specifically, we are interested in understanding and controlling biological interactions of polymers with cells at the nano-scale. The fundamental understanding will lead us to more translational cancer research fields including: i) Targeted drug delivery with enhanced targeting efficacy using newly designed nanocarriers; ii) Local, transdermal delivery of drugs such as chemo-preventive medicine; and iii) Biomimetic multifunctional devices for effective detection and isolation of rare cells such as circulating tumor cells (CTCs).
From left to right, Seungpyo Hong, Ashley Cha, Jason Bugno, Suhair Sunoqrot, Ryan Pearson, Yang Yang, Kevin Tam, Jeeho Lee, Hao-jui Hsu, Frehiwot Gebrehiwot, Matthew Pasco, Ja Hye Myung
Missing members: Marilyn Gaske
Dr. Hong joins N.I.C.E. Meeting held in Nice, France to give a talk related to our biomimetic approaches for effective capture and isolation of circulating tumor cells.
Dr. Hong visits the University of North Carolina at Chapel Hill to give a seminar at the Radiation Oncology Department.
Our paper entitled "Poly(ethylene glycol) Corona Chain Length Controls End-Group-Dependent Cell Interactions of Dendron Micelles" is accepted for publication in Macromolecules! The authors are the first author Hao-jui, Soumyo, Ryan, Sayam, Dr. Kral, and Dr. Hong. This is the 50th paper published by Dr. Hong. Congratulations!
Ryan successfully defends his PhD disseration, becoming the 4th PhD from the group. Congratulations, Dr. Pearson!!!
Dr. Hong promotes to Associate Professor with Indefinite Tenure. He is also appointed as Director of Graduate Eduation for the College of Pharmacy. Congratulations!
NSF supports our hybrid nanoparticle project for next three years!
Dr. Hong delivers a featured invited talk at The 46th Pharmaceutics Graduate Student Research Meeting (PGSRM) held in Chicago hosted by UIC College of Pharmacy.
Dr. Hong Y. Cho from Carnegie Mellon University joins our lab as a Postdoctoral Associate He recently finished his PhD working with Prof. Krzysztof Matyjaszewski in the Chemistry Department of CMU. Welcome Dr. Cho!
Our paper entitled "Differential Detection of Tumor Cells using A Combination of Cell Rolling, Multivalent Binding, and Multiple Antibodies" is being accepted for publication by Analytical Chemistry! The authors are Ja Hye, Khyati, Dr. Chen, Dr. Molokie, and Dr. Hong. Congratulations!
Our paper entitled "Prolonged Blood Circulation and Enhanced Tumor Accumulation of Folate-Targeted Dendrimer-Polymer Hybrid Nanoparticles" is being accepted for publication by the Journal of Controlled Release! The authors are Suhair, Jason, Daniel, Dr. Burdette and Dr. Hong. Congratulations!
Our paper (Yang et al) published in Advanced Functional Materials is highlighted as Frontispiece by the journal!
Dr. Hong travels to Asia to give a series of invited talks. He gives a keynote speech at the 2014 International Conference on Mechanics and Materials Engineering (ICMME), held in Xi'an, China. He also visits and gives invited seminars at POSTECH in Pohang, Korea; Donghua University in Shanghai, China; and Nanyang Technological University and National University of Singapore in Singapore