IPRM Funding
Active
| Investigator(s) | Type/Title | Total Dollars* |
Joe G.N. Garcia, MD; Steven M. Dudek, MD; V. Natarajan, PhD |
PPG (NIH), 2008–2013 |
$ 11,806,085 |
V. Natarajan, PhD; |
PPG (NIH), 2011-2016 Role of Sphingolipids in the Pathobiology of Lung Injury |
$ 11,700,000 |
| Joe G.N. Garcia, MD | R01 (NIH), 2008-2012 Regulation of Asthmatic Inflammation by Non-Muscle MLCK |
$2,215,043 |
| Joe G.N. Garcia, MD | R01 (NIH), 2009-2013 Pathogenic Mechanisms of PBEF in Ventilator Induced Lung Injury |
$2,041,675 |
| Joe G.N. Garcia, MD (Aqualung Therapeutics, Corp) |
SBIR (NIH), 2011-2013 PBEF Neutralizing Humanized Monoclonal Antibodies As Novel Therapeutic Approaches |
$250,000 |
| Viswanathan Natarajan, PhD | R37 MERIT AWARD (NIH), 2004-2014 Protective Role of Intracellular S1P in Lung Injury |
$3,925,000 |
| Jason X.-J. Yuan, MD/PhD | P01 (NIH), 2010-2015 Genetic and Molecular Mechanisms in Hypoxia-Induced Pulmonary Hypertension |
$1,872,245 |
Steven M. Dudek, MD |
R01 (NIH), 2007-2012 |
$ 1,918,750 |
| Jeffrey R. Jacobson, MD | R01 (NIH), 2009-2013 Integrin β4 in Vascular Inflammatory Responses |
$1,962,500 |
| Roberto Machado, MD | K-23 (National Heart Lung & Blood Institute), 2010-2015 Carbon Monoxide Therapy for Severe Pulmonary Arterial Hypertension |
$650,000 |
| Ting Wang, PhD & Joe G.N. Garcia, MD |
Parker B. Francis Fellowship, 2012-2015 Mechanisms of Particulate Matter-Induced Cardiac Arrhythmias |
$156,000 |
| Roberto Machado, MD; Gregory Thatcher, PhD; Tom Driver, PhD | Areas of Excellence Phase 2 Award (UIC), 2012 Development of Novel Inhibitors of PBEF/NAMPT to Treat Pulmonary Arterial Hypertension |
$100,000 |
| Julian Solway, MD & Joe G.N. Garcia, MD |
Roadmap CTSA (NIH), 2007-2012 Re-engineering Translational Research at the University of Chicago |
$2,607,700 |
| Patrick Singleton,PhD & Joe G.N. Garcia, MD |
R01 (NIH), 2009-2013 Hyaluronan and CD44 are Novel Targets for Acute Lung Injury |
$1,950,000 |
| Augustine Choi, MD & Joe G.N. Garcia, MD |
U01 (NIH), 2011–2014 Carbon Monoxide for Idiopathic Pulmonary Fibrosis |
$225,000 |
Pending
| Investigator(s) | Type/Title | Total Dollars* |
| Joe G.N. Garcia, MD; Steven M. Dudek, MD; V. Natarajan, PhD; Jeffrey Jacobson, MD |
PPG (NIH), Pending Cytoskeletal Regulation of Lung Endothelial Pathology |
$16,000,000 |
| Jeffrey Jacobson, MD | R01 (NIH), Pending Gadd45a Mediates Acute Lung Injury via Akt |
$1,900,000 |
Ting Wang, PhD & |
R01 (NIH), Pending Mechanisms of Particulate Matter-Induced Cardiac Arrhythmias |
$1,900,000 |
Support/Sponsor
| Investigator(s) | Type/Title | Total Dollars* |
| Rachel Wolfson, MD | K-08 (National Heart Lung & Blood Institute), 2008-2013 Role of HMGB1 and RAGE Receptors in Acute Inflammatory Lung Injury |
$695,000 |
Past (Select)
| Investigator(s) | Type/Title | Total Dollars* |
| Joe G.N. Garcia, MD & Roy Brower, MD | SCCOR (NIH), 2003–2008 Molecular Approaches to Ventilator-Associated Lung Injury: Novel Therapies for VALI-Induced Vascular Leak |
$1,110,930 |
| Joe G.N. Garcia, MD | PPG (NIH), 2003–2008 Cytoskeletal Regulation of Lung Endothelial Pathobiology |
$7,878,593 |
| Joe G.N. Garcia, MD | PPG (NIH), 1998–2003 Molecular Regulation of Endothelial Cell Permeability |
$5,984,000 |
| Joe G.N. Garcia, MD & Jon S. Samet, MD |
EPA/Johns Hopkins, 2005–2010 (extended to 2011) Health Effects of Particulate Matter |
$925,000 |
| Joe G.N. Garcia, MD | ARRA (NIH), 2010-2011 American Recovery and Reinvestment Act |
$746,743 |
| Shui Q. Ye, PhD & Joe G.N. Garcia, MD |
R01 (NIH), 2006–2011 Novel Role of PBEF in Acute Lung Injury |
$191,875 |
| Alexander Verin, PhD & Joe G.N. Garcia, MD |
R01 (NIH), 2006-2011 ATP in Amelioration of Acute lung Injury and Permeability |
$95,938 |
| Joe G.N. Garcia, MD & Jenny Van Eyck, PhD | U01 (NIH), 2002–2009 NHLBI Program in Proteomics - Post-Translational Modification of Endothelial Cell Myosin Light Chain Kinase |
$560,000 |
| Joe G.N. Garcia, MD & Victor R. Gordeuk, MD | R01 (NIH/Howard University), 2005–2009 Sickle Cell Anemia - Insights into Pulmonary Hypertension |
$515,200 |
| Viswanathan Natarajan, PhD | R01 (NIH), 2006-2011 Nox 4 in Endothelial Cell ROS Production, Signaling and Motility |
$1,862,170 |
*Estimated