The Institute for Personalized
Respiratory Medicine

University of Illinois Medical Center, Chicago


Mission and Overall Goals

The mission of the Institute for Personalized Respiratory Medicine (IPRM) at the University of Illinois at Chicago (UIC) and University of Illinois Hospital & Health Sciences System in Chicago is to deliver personalized medicine to medically underserved populations afflicted with a variety of cardiopulmonary disorders. The overall goals of IPRM are to enhance understanding of cardiovascular and respiratory health and diseases through collaborative basic, translational and clinical investigation. The eventual outcome of these efforts is the development of novel strategies and therapies to improve care and health of the medically underserved. The Institute's focus will include lung disorders such as acute- and sub-acute lung injury, infectious lung disease, interstitial lung diseases (such as sarcoidosis and idiopathic pulmonary fibrosis), pulmonary hypertension, sickle cell lung disease, scleroderma, lung cancer, asthma, and environmental lung disorders. Additional efforts are devoted to cardiac disorders including cardiac sarcoidosis, heart failure and lung and cardiac transplantation complications.

IPRM Group

To accomplish these goals, IPRM will leverage the substantial expertise of the multi-disciplinary group of outstanding IPRM investigators who are expert in basic and translational research as well as clinical investigation which will employ novel IPRM-derived therapies. IPRM will recruit new tenure-track and non-tenure track faculty and post-doctoral fellows to provide an infrastructure and supportive environment to develop innovative research programs thereby ensuring a vibrant pipeline of future thought-leaders who are similarly committed to improving the care of the underserved with cardio-respiratory disorders.

The Institute infrastructure will promote the development of synergistic and inter-disciplinary translational research programs through multi-disciplinary and multi-departmental efforts and core units in genomics, genetics, proteomics, lipidomics, cell culture, molecular biology, imaging, and bioinformatics. The Institute will strive to develop interactions and leverage the many strengths within clinical departments and basic science disciplines across University of Illinois education programs. The Institute will support research activities of graduate students, post-doctoral fellows (PhDs) and clinical fellows (MDs) and expand the currently funded NIH training programs, RO1s and PPGs within IPRM as well available within various participating Departments and Centers. Finally, IPRM will serve as the academic home for the nurturing of the physician scientists engaged in translational cardiopulmonary research in their successful transition to an independent scientist. We anticipate that in rapid fashion that the Institute of Personalized Respiratory Medicine will be a nationally recognized entity and a model for the conduct of multidisciplinary translational research which impacts the delivery of personalized medicine to the medically underserved.

Director

Co-Director

Joe G.N. "Skip" Garcia, MD (jggarcia@uic.edu)
Viswanathan Natarajan, PhD (visnatar@uic.edu)
Joe G.N. "Skip" Garcia, MD

Vice President for Health Affairs
Earl M. Bane Professor of Medicine
Viswanathan Natarajan, PhD

Professor of Pharmacology and
Pulmonary Medicine


Principal Investigators

Jason X.-J. Yuan, MD/PhD (jxyuan@uic.edu) Steven M. Dudek, MD (sdudek@uic.edu) Evgeny Berdyshev, PhD (eberdysh@uic.edu) Jeffrey Jacobson, MD (jrjacob@uic.edu) Roberto Machado, MD (machador@uic.edu)
Jason X.-J. Yuan,
MD, PhD


Professor of
Medicine &
Pharmacology
Steven M. Dudek,
MD


Associate Professor
of Pulmonary
Medicine
Evgeny Berdyshev,
PhD


Assistant Professor
of Pulmonary
Medicine
Jeffrey R. Jacobson,
MD


Associate Professor
of Pulmonary
Medicine
Roberto F. Machado,
MD


Associate Professor
of Pulmonary
Medicine



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