Recent Publications
Lipton HL, Liang Z, Son K-N, Hertzler S. (2007) A specific viral cause of multiple sclerosis: 1 disease, 1 virus. Ann Neurol. (In Press).
Groothuis DR, Vavra MW, Schlageter KE, Kang EW-R, Itskovich A, Hertzler S, Allen CV, Lipton HL. (2007) Efflux of drugs and solutes from the brain: The interactive roles of diffusional transcapillary transport, bulk flow and capillary transporters. J Cereb Blood Flow Metab. 27:43-56.
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Lipton, HL, Kumar ASM, Hertzler S. "Cardioviruses: Encephalomyocarditis virus (EMCV) and Theiler's murine encephalomyelitis virus (TMEV)." In: J Fox, S Barthold, MI Davisson, eds. The Mouse in Biomedical Research. 2nd ed. San Diego: Elsevier/Academic Press, 2007.
Kincaid O, Lipton HL. Viral Myelitis: an update. Curr Neurol Neurosci Rep. 2006 Nov;6(6):469-74.
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Lipton HL. B lineage cells in inflammatory central nervous system. Ann Neurol. 2006 Oct;60(4):486-7; author reply 487.
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Groothuis DR, Vavra MW, Schlageter KE, Kang EW, Itskovich AC, Hertzler S, Allen CV, Lipton HL. Efflux of drugs and solutes from brain: the interactive roles of diffusional transcapillary transport, bulk flow and capillary transporters. J Cereb Blood Flow Metab. 2006 Apr 12.
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Lipton HL, Kumar AS, Hertzler S, Reddi HV. Differential usage of carbohydrate co-receptors influences cellular tropism of Theiler's murine encephalomyelitis virus infection of the central nervous system. Glycoconj J. 2006 Feb;23(1-2):39-49.
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Rubio N, Sanz-Rodriguez F, Lipton HL. Theiler's virus induces the MIP-2 chemokine (CXCL2) in astrocytes from genetically susceptible but not from resistant mouse strains. Cell Immunol. 2006 Jan;239(1):31-40.
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Lipton HL, Kumar AS, Trottier M. Theiler's virus persistence in the central nervous system of mice is associated with continuous viral replication and a difference in outcome of infection of infiltrating macrophages versus oligodendrocytes. Virus Res. 2005 Aug;111(2):214-23.
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Lipton HL, Kallio P, Jelachich ML. Simplified quantitative analysis of spinal cord cells from Theiler's virus-infected mice without the requirement for myelin debris removal. J Immunol Methods. 2005 Apr;299(1-2):107-15.
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Lipton HL, Kumar AS, Hertzler S, Reddi HV. Differential usage of carbohydrate co-receptors influences cellular tropism of Theiler's murine encephalomyelitis virus infection of the central nervous system. Glycoconj J. 2006 Feb;23(1-2):39-49.
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Jelachich ML, Reddi HV, Trottier MD, Schlitt BP, Lipton HL. Susceptibility of peritoneal macrophages to infection by Theiler's virus. Virus Res. 2004 Sep 1;104(2):123-7.
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Reddi HV, Kumar AS, Kung AY, Kallio PD, Schlitt BP, Lipton HL. Heparan sulfate-independent infection attenuates high-neurovirulence GDVII virus-induced encephalitis. J Virol. 2004 Aug;78(16):8909-16.
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Kumar AS, Reddi HV, Kung AY, Dal Canto M, Lipton HL. Virus persistence in an animal model of multiple sclerosis requires virion attachment to sialic acid coreceptors. J Virol. 2004 Aug;78(16):8860-7.
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Trottier M, Schlitt BP, Kung AY Lipton HL. (2004) Transition from acute to persistent Theiler's virus infection requires active viral replication that drives proinflammatory cytokine expression and chronic demyelinating disease. J Virol. 78:12480-12488.
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Kumar AS, Kallio P, Luo M, Lipton HL. Amino acid substitutions in VP2 residues contacting sialic acid in low-neurovirulence BeAn virus dramatically reduce viral binding and spread of infection. J Virol. 2003 Feb;77(4):2709-16.
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Schlitt BP, Felrice M, Jelachich ML, Lipton HL. Apoptotic cells, including macrophages, are prominent in Theiler's virus-induced inflammatory, demyelinating lesions. J Virol. 2003 Apr;77(7):4383-8.
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Shah AH, Lipton HL. Low-neurovirulence Theiler's viruses use sialic acid moieties on N-linked oligosaccharide structures for attachment. Virology. 2002 Dec 20;304(2):443-50.
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Reddi HV, Lipton HL. Heparan sulfate mediates infection of high-neurovirulence Theiler's viruses. J Virol. 2002 Aug;76(16):8400-7. Erratum in: J Virol. 2003 Aug;77(16):9106.
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Trottier M, Schlitt BP, Lipton HL. Enhanced detection of Theiler's virus RNA copy equivalents in the mouse central nervous system by real-time RT-PCR. J Virol Methods. 2002 May;103(1):89-99.
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Hertzler S, Kallio P, Lipton HL. UDP-galactose transporter is required for Theiler's virus entry into mammalian cells. Virology. 2001 Aug 1;286(2):336-44.
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Trottier M, Kallio P, Wang W, Lipton HL. High numbers of viral RNA copies in the central nervous system of mice during persistent infection with Theiler's virus. J Virol. 2001 Aug;75(16):7420-8.
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Jelachich ML, Lipton HL. Theiler's murine encephalomyelitis virus induces apoptosis in gamma interferon-activated M1 differentiated myelomonocytic cells through a mechanism involving tumor necrosis factor alpha (TNF-alpha) and TNF-alpha-related apoptosis-inducing ligand. J Virol. 2001 Jul;75(13):5930-8.
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Lipton HL, Kim BS, Yahikozawa H, Nadler CF. Serological evidence that Mus musculus is the natural host of Theiler's murine encephalomyelitis virus. Virus Res. 2001 Jul;76(1):79-86.
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