CURRICULUM VITAE

Gary Matthew Klein

 

The University of Illinois at Chicago

The Center for Pharmaceutical Biotechnology and

The Department of Medicinal Chemistry and Pharmacognosy

900 South Ashland Avenue (M/C 870)

Chicago, IL 60607

Lab Phone:  (312) 996-1687

Fax:  (312) 413-9303

Email:  gklein1@uic.edu

        

HOMETOWN     

Grand Rapids, MI

                                          

GRADUATE RESEARCH PROJECT

 

I am currently investigating the structure and function of essential enzymes from Bacillus anthracis (anthrax) that may serve as useful drug targets for structure-based drug design.  I am also actively involved in military training in the United States Army.   I plan to ultimately become an Active Duty Commissioned Officer in the United States Army, Medical Service Corps.

                

EDUCATION     

 

University of Illinois – Chicago                        Chicago, IL

Ph.D. Candidate (Medicinal Chemistry)             2003-Current

Overall GPA: 3.8/4.0

 

University of Michigan                                     Ann Arbor, MI

B.S. in Biochemistry with Honors                     May, 2003

Overall GPA: 3.4/4.0

 

 

RELATED EXPERIENCE

 

University of Illinois at Chicago, Department of Medicinal Chemistry

Ph.D. Candidate                                     2003-Current                      

Project: “Enoyl-Reductase (FabI) as a Target for Antibiotics.”

 

University of Michigan                            Ann Arbor, MI

Department of Chemistry

Undergraduate Researcher                     2000-2003

Undergraduate Honors Thesis Topic: Development of Protamine-Releasing Polymer Films as a Titrant Delivery System for the Potentiometric Determination of Heparin

Assisted in animal studies relating to the in vivo release of nitric oxide from polymeric-films coating arterially implanted oxygen sensors.

 

 

HONORS & AWARDS

 

*     Bauer Ludwig Fellowship                                               2004

*     University Fellowship, Univ. of Illinois – Chicago            2003-2007

*     Alumni Summer Research Fellowship                             2002

*     Amoco Foundation Summer Research Fellowship            2001

*     University of Michigan’s LS&A Honors College                1999-2003

*     University Honors (x3), University of Michigan

 

LEADERSHIP EXPERIENCE

 

United States Army Reserve                   Fort Sheridan, IL

801st Combat Support Hospital (CSH)             

                 Platoon Leader

                 Clinical Laboratory Section, Officer in Charge    2004-Current

Responsible for developing basic soldier skills in my PLT of 45 Soldiers.

                

Army ROTC

Fire Batallion                                         Chicago, IL

Army Officer Cadet

Acted as MSI/II Class Coordinator           2003-Current

ROTC Committees (ROCOM) Chairman    2004-Current

 

TEACHING EXPERIENCE

 

University of Illinois at Chicago               2004-Current

Teachers Assistant               

Principles of Drug Action and Theraputics (PDAT) 402

Principles of Drug Action and Theraputics (PDAT) 403

 

ABSTRACTS & POSTER PRESENTATIONS

 

  1. “Protamine-Releasing Films as Titrant Delivery System for the Potentiometric Determination of Heparin,” (2002) Pittsburgh Conference. New Orleans, LA

 

  1. “Development of Protamine-Releasing Polymeric Films,” (2001) REU Research Presentation. Clevland, OH

 

  1. ORAL PRESENTATIONS

 

  1. Literature Seminar. “The Type II Fatty Acid Synthase (FAS) System as a Target for Antibiotics,” University of Illinois – Chicago. Chicago, IL

 

CONFERENCES ATTENDED

 

*     Midwest Enzyme Chemistry Conference XXIV                October, 2004

*     Annual MIKI meeting (Medicinal Chemistry)                   April, 2004

*     REU Research Presentation (Kent State Univ)                August, 2002

*     Pittsburgh Conference (PITTCON)                                  March, 2002

*     REU Research Presentation (John Carrol Univ)               August, 2001

*     Great Lakes/Central Regional ACS Meeting                    June, 2001

 

LABORATORY SKILLS AND TECHNIQUES

        

*     Cloning and construction of expression vectors

*     Optimizing of expression conditions

*     Protein Purification- column chromatography

*     Gel chromatography (SDS PAGE and Agarose DNA gels)

*     Crystallization

*     UV/Visible Spectroscopy

*     Potentiometry