Research goals: To elucidate the pathophysiology of psychiatric disorders which lead to suicide, including mood disorders and schizophrenia. These studies will be conducted by the examination of genetic and transcriptional variation in patients relative to comparison groups. Through these investigations, we aim to identify novel biochemical targets for improved psychotropic medication and biological markers to facilitate diagnosis.

Current Lab Members

Monsheel Sodhi

Monsheel's areas of interest include the contribution of genetic, epigenetic, and post-transcriptional variation to the etiologies of major psychiatric disorders and suicide, as well as the pharmacogenetics of schizophrenia and mood disorders. She obtained her Bachelor of Pharmacy and her PhD at the University of London, and completed her postdoctoral training at the University of Oxford and Vanderbilt University.

Evelyn Nwabuisi-Heath

Evelyn has recently joined the Sodhi Lab as a Postdoctoral Research Fellow. She completed her PhD at University of Illinois at Chicago. During her graduate work, she investigated the mechanisms of apolipoprotein E isoform effects on glutamatergic synapses and Alzheimer's disease. She is interested in studying the role of altered ADAR enzyme activity in glutamatergic synaptic dysregulation and neuropsychiatric disorders.

Angel Gray

Angel has recently joined the Sodhi Lab as a Postdoctoral Research Fellow. Angel completed both her BS in Psychology and Neuroscience and her PhD at Loyola University Chicago, IL. During her graduate work, she studied AVE5026, a new hemisynthetic ultra low molecular weight heparin (ULMWH) with enriched anti-Xa activity and enhanced antithrombotic activity, using various animal models. Wanting to switch research focus, Angel joined the Sodhi lab in order to do more neuroscience/psychology related research. She is interested in studying the molecular mechanisms that underlie psychological disorders such as schizophrenia, depression, and suicide.

Michelle Vierra

Michelle joined the Sodhi lab in January 2012 and earned her Bachelor's of Science degree in Biological Sciences from UIC. She studies the expression of ADAR enzymes in psychiatric disorders in the Sodhi lab and is interested in further studying the molecular pathophysiology of psychiatric disorders in graduate school.

Yoshimi Nomura

Yoshimi is an undergraduate student of Biological Sciences at University of Illinois at Chicago and studies the expression of GRIA3 in psychiatric disorders. Yoshimi plans to pursue a career in Pharmacy.

Chris Qin

chris

Chris is a graduate student at the UIC Department of Bioengineering. Chris is interested in identifying gene expression signatures of psychiatric disorders in collaboration with the Sodhi lab and is expecting to receive his Doctorate in Bioinformatics in 2014.

Braden Lenz

braden

Braden joined the Sodhi lab in September 2012 and is completing his undergraduate studies in mathematics and computer science at UIC. Braden is most interested in software engineering, computational systems, and computational complexity within the scope of bioinformatics. He is designing software to aid in the genetic analyses and aspires to be a computer scientist.

Sean Munoz

sean

Sean is a second year MD student at the UIC College of Medicine where he is expected to graduate in May 2016. He recently joined the lab as part of the UIC College of Medicine’s Hispanic Center of Excellence research program. He is interested in neuroscience research regarding the underlying molecular mechanisms of behavioral disorders such as schizophrenia and aspires to be a physician-scientist.

Jennifer Melbourne

jenni

Jenni recently joined the Sodhi lab and is interested in researching the mechanisms underlying schizophrenia and psychosis. She completed her undergraduate degree in Neuroscience at Cardiff University and her Master's degree in Mind, Language, and Embodied Cognition at the University of Edinburgh.

Julie Do

Julie is currently a student at UIC. She is working towards an undergraduate degree in Biochemistry which will be completed in the Spring of 2014. After graduation, Julie hopes to attend Pharmacy school and pursue a career in Pharmacy. Julie is also interested in gaining lab research experience and learning about major health issues on a molecular level.

 

Lab Alumni

Anna Bobrowska

Anna was a Postdoctoral Research Fellow in the Sodhi Lab and has interest in unravelling the molecular mechanisms that underlie disorders of the CNS. She completed in MSc in Molecular Biology at the International Max Planck Research school in Goettingen, Germany and her PhD at King's College London, UK. She is currently in a postdoctoral role at Northwestern University in Evanston.

Julie Bucek

Julie is a PharmD student at the UIC College of Pharmacy expected to graduate in May 2015. She is interested in pharmacogenetics and its relevance to the treatment of depression. She plans to continue her training in both a PGY1 and PGY2 residency in order to practice as a clinical psychiatric pharmacist in the future.

Jack Bostrom

Jack joined the lab in the summer of 2010 and graduated from Gettysburg College in May 2011 with a BS in Biology and a minor in Chemistry. He is attending medical school at the University of Massachusetts.

Kavita Nadendla

Kavita has conducted research on glutamate receptor RNA editing in the Sodhi Lab. She completed degrees in both Biology and Neuroscience, and began Medical School in the Fall of 2012. Kavita was awarded the distinction of Outstanding Student for 2012 by the UAB Undergraduate Neuroscience Program due to her excellent grades and participation in undergraduate research.

Jakub Tucholski

Jakub studied Economics at the University of Chicago and performed molecular genetic analyses of schizophrenia in the Sodhi Lab.

Daniel Mount

Daniel graduated from UAB with a BS in Psychology in May, 2010. He has conducted a variety of genetic and transcriptional experiments in postmortem human tissue and drug-treated animals.

 

Important Dates

3/14/13: CPB & Pharmacy Practice Seminar: "Estrogen, Depression, and Hippocampal Function". Lori L. McMahon, PhD. 12PM, 3rd Floor Library MBRB.

4/18/13: CPB & UICENTRE Seminar "Allosteric Modulators of GPCRs as a Novel Approach to Treatment of CNS Disorders". Jeff Conn, PhD. 12PM, 3rd Floor Library MBRB.

5/02/13: CPB & Pharmacy Practice Seminar "Genetic Variation and Alternative Transcripts in Human Brain Development and Schizophrenia". Joel E. Kleinman, PhD. 12PM, 3rd Floor Library MBRB.

9/12/13: CPB Seminar "Effects of G-Protein Coupled Receptors on Vessicle Fusion". Simon Alford, PhD. 12PM, 3rd Floor Library MBRB..

9/19/13: CPB Seminar "TBD". Janet Richmond, PhD. 12PM, 3rd Floor Library MBRB.

11/09/13-11/13/13: Society for Neuroscience Annual Meeting; San Diego, CA.