Research goals: To elucidate the pathophysiology of psychiatric disorders which lead to suicide, including mood disorders and schizophrenia. These studies will be conducted by the examination of genetic and transcriptional variation in patients relative to comparison groups. Through these investigations, we aim to identify novel biochemical targets for improved psychotropic medication and biological markers to facilitate diagnosis.

Current Lab Members

Monsheel Sodhi

Monsheel's areas of interest include the contribution of genetic, epigenetic, and post-transcriptional variation to the etiologies of major psychiatric disorders and suicide, as well as the pharmacogenetics of schizophrenia and mood disorders. She obtained her Bachelor of Pharmacy and her PhD at the University of London, and completed her postdoctoral training at the University of Oxford and Vanderbilt University.

 

Michelle Vierra

Michelle joined the Sodhi lab in January 2012 and is finishing her undergraduate studies in biological sciences at UIC. She is studying expression of ADAR enzymes in psychiatric disorders in the Sodhi lab and aspires to be a medical scientist.

 

Angel Gray

Angel Gray has recently joined the Sodhi Lab as a Postdoctoral Research Fellow. Angel completed both her B.S in Psychology and Neuroscience and her Ph.D at Loyola University Chicago, IL. During her graduate work, she studied AVE5026, a new hemisynthetic ultra low molecular weight heparin (ULMWH) with enriched anti-Xa activity and enhanced antithrombotic activity, using various animal models. Wanting to switch research focus, Angel joined the Sodhi lab in order to do more neuroscience/psychology related research. She is interested in studying the molecular mechanisms that underlie psychological disorders such as schizophrenia, depression, and suicide.


Anna Bobrowska

Anna Bobrowska has recently joined the Sodhi Lab as a Postdoctoral Research Fellow. Anna completed her MSc in Molecular Biology at the International Max Planck Research School in Goettingen,Germany and her PhD at King's College London, UK. So far, she has worked with the worm C.elegans studying PIP kinases and phosphatases as well as with mice, investigating the validity of tubulin deacetylases HDAC6 and SIRT2 as targets for treatment of Huntington's disease. She is interested in unravelling the molecular mechanisms that underlie disorders of the central nervous system.

 

Julie Bucek

Julie is a PharmD student at the UIC College of Pharmacy expected to graduate in May 2015. She is interested in pharmacogenetics and its relevance to the treatment of depression. She plans to continue her training in both a PGY1 and PGY2 residency in order to practice as a clinical psychiatric pharmacist in the future.

 

Yoshimi Nomura

Yoshimi Nomura is an undergraduate student of Biological Sciences at UIC, with plans to pursue a career in Pharmacy.

 

Chris Qin

Chris is a graduate student at the UIC Department of Bioengineering. Chris is interested in identifying gene expression signatures of psychiatric disorders in collaboration with the Sodhi lab and is expecting to receive his Doctorate in Bioinformatics in 2014.

 

Braden Lenz

Braden joined the Sodhi lab in September 2012 and is completing his undergraduate studies in mathematics and computer science at UIC. Braden is most interested in software engineering, computational systems, and computational complexity within the scope of bioinformatics. He is designing software to aid in the genetic analyses and aspires to be a computer scientist.

 

Lab Alumni

Jack Bostrom

Jack joined the lab in the summer of 2010 and graduated from Gettysburg College in May 2011 with a BS in Biology and a minor in Chemistry. He is attending medical school at the University of Massachusetts.

 

Kavita Nadendla

Kavita Nadendla has conducted research on glutamate receptor RNA editing in the Sodhi Lab. She completed degrees in both Biology and Neuroscience, and began Medical School in the Fall of 2012. Kavita was awarded the distinction of Outstanding Student for 2012 by the UAB Undergraduate Neuroscience Program due to her excellent grades and participation in undergraduate research.

 

Jakub Tucholski

Jakub studied Economics at the University of Chicago and performed molecular genetic analyses of schizophrenia in the Sodhi Lab.

 

Daniel Mount

Daniel Mount graduated from UAB with a BS in Psychology in May, 2010. He has conducted a variety of genetic and transcriptional experiments in postmortem human tissue and drug-treated animals.

Important Dates

4/19/12: CPB Department Seminar: "Control of energy metabolism by editing of serotonin receptor mRNAs". Kazuko Nishikura. 12PM, 1st Floor Auditorium MBRB.

2/22/12: BPS Department Seminar "Disrupted RNA Editing of the Glutamate and Serotonin Systems in Psychiatric Disorders." PHAR 134-3.

12/5/11 - 12/9/11: 50th Annual Meeting for the American College of Neuropsycho- pharmacology (ACNP).

11/12/11 - 11/16/11: Society for Neuroscience Annual Meeting (SfN).

9/28/11: UAB Psychology Colloqium Series Presentation: "Decoding Mixed Messages in Schizophrenia and Depression."