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The Following major services are offered by the TRL |
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General Toxicology and Pharmacokinetics CAPABILITIES Ph.D.,
M.D., and D.A.B.T. Study Directors |
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Analytical Chemistry and Bioanalysis CAPABILITIES GLP
compliance |
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CLINICAL TRIALS CAPABILITIES •
Several
hundred IRB protocols approved and studies conducted •
Hundreds of
UIC professors and top medical specialists involved
in clinical trials •
Accommodate research
subjects of all ages, from newborn to geriatric populations •
Accommodate
adult psychiatric subjects, outpatient psychiatry studies involving children •
Examination and procedure rooms •
Outpatient area •
Inpatient rooms •
Specimen processing laboratory •
Radioisotope laboratory •
Physiology laboratory •
Adult psychiatry beds •
A metabolic kitchen can provide special
diets designed, calculated and prepared under supervision of the staff
dietitian •
A database management system office Nursing Staff •
Provides a
core of nursing professionals 24/7 •
Certified
nurses provide drug administration •
Performs all
necessary medical procedures and collects data •
Nursing staff also
can be sent to other areas of the hospital/university to collect research
data Laboratory •
Processing of study samples •
Shipping of specimens •
Laboratory clinical chemistry analyses •
A radioisotope laboratory facility
available for radioisotope studies. •
-20°C to -80°C refrigeration •
DNA extraction service •
Cell / Tissue incubation •
Cell Separation facilities Investigational Pharmacy •
Assures appropriate storage, handling, drug
accountability, information access and compliance with regulations including FDA •
UIC Investigational pharmacist disperses
all drugs •
Drugs accessibility 24/7 •
Provides blinded medication dosage forms
for placebo-controlled studies •
Aseptically prepares intravenous products
(class 10,000) • Prepares dietary supplements if needed The •
Study design •
Quantification
and measurement issues •
Mathematical
modeling •
Simulation
studies |
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Reproductive and Developmental Toxicology CAPABILITIES Ph.D.
Study Directors |
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Pharmacology Research CAPABILITIES GLP Compliance if
requested
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Genomics
CAPABILITIES •
Affymetrix GeneChip
Array Hybridization Scanning and Data Acquisition •
Glass Slide Array Hybridization •
Real-time Quantitative RT-PCR Analysis •
Human IMAGE cDNA Clone Selection of
40,000 Sequence-Verified Clones •
Custom Glass Slide Array Preparation •
Bioinformatics Support: Assistance
with Experimental Design Data Analysis and
Functional Annotation Equipment •
Affymetrix GeneChip
System •
OmniGrid Accent micro-array spotter
(Genomic Solutions) •
BioRobot 8000 (Qiagen)
•
Primus multi-block system for high-throughput PCR (MWG) •
Confocal dual-laser scanner ScanArray Lite (Packard BioChip) •
ABI PRISM® 7900HT Sequence Detection System Software •
GeneSpring (Silcon
Genetics) •
Spotfire DecisionSite
software (Spotfire, Inc) •
Pathway Assist (Ariadne Genomics) •
ScanArray and QuantArray
(Packard BioChip) •
MicroDB software and data mining tool (Affymetrix)
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Affymetrix Microarray
Suite (Affymetrix) • More at : http://www.uic.edu/depts/rrc/cgf/index.html |
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Proteomics CAPABILITIES •
Ciphergen SELDI-TOF platform •
Novex, BioRad, and Pharmacia
1-D & 2-D Gel Electrophoresis Systems •
Bio-Rad Proteomeworks
Spot Cutter •
Bio-Rad FX Pro Plus Multi-Imager System •
ABI Voyager DE-Pro MALDI-TOF Mass Spectrometer •
Hewlett-Packard (HP) 1100 liquid chromatograph using MSD ion trap XCT
with on-line nano LC and nano
electrospray ion source (Agilent
Technologies, Palo Alto, CA) for a 75 μm
column optimized format LC/MS/MS with Spectrum Mill software. •
Isotope-coded affinity tag (ICAT) method |
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Download a detailed
document on the services
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