3D Molecular Designs & MSOE Center for BioMolecular Modeling #226 1025 N. Broadway Milwaukee WI 53202 Tel: 414-331-0847 Fax: 414-774-3435 Email: heather_ryan@antiochsea.edu Web: www.3dmoleculardesigns.com Provide innovative molecular models and professional development opportunities for educators in the biosciences. 3DMD uses rapid prototyping technologies to design molecular models based on atomic coordinates. Through its professional development programs, the CBM involves educators in the design and construction of physical models for use in teaching. 3DMD sells magnetic water and DNA kits, protein modeling toobers, and protein models. Accelrys #114 9685 Scranton Road San Diego CA 92121 Tel: 858-799-5711 Fax: 858-799-5777 Email: bevb@accelrys.com Web: www.accelrys.com A leading provider of simulation and informatics tools to accelerate the discovery and development of new pharmaceuticals and chemicals. Our solutions enhance scientific insight and promote the flow of information and knowledge throughout your discovery program, supporting your decision making process and enabling intelligent use of resources. Area Detector Systems #106,108 12550 Stowe Drive Poway CA 92064 Tel: 858-486-0618 Fax: 858-486-0294 Email: th@adsc-xray.com Web: www.adsc-xray.com CCD detector x-ray system for protein crystallography applications. Art Robbins Instruments #101 1293 Mountain View Alviso Road Suite D Sunnyvale CA 94089 Tel: 408-734-8400 Fax: 408-734-8420 Email: Web: Automated Micro/Nano Dispenser for 96 well crystallography plates. Also showing 96 well intelliplates. Biophysics Collaborative Access Team (BioCAT) #319 Argonne National Laboratory BioCAT/APS, Sector 18, Bldg. 435B 9700 S. Cass Ave. Argonne IL 60439 Tel: 630-252-0549 Fax: 630-252-0545 Email: krolik@bio.aps.anl.gov Web: www.bio.aps.anl.gov The Biophysics Collaborative Access Team (BioCAT) operates a NIH supported Biotechnology Research Resource for the study of the structure and dynamics of non-crystalline biological materials at the Advanced Photon Source, Argonne, IL. The goal of such research is to determine the detailed mechanism of action of biological systems at the molecular level. The techniques employed are static, time and spatially resolved x-ray diffraction, x-ray scattering and x-ray absorption/emission spectroscopy. Projects are invited from all scientists who can benefit from our advanced capabilities. Blake Industries #112 660 Jerusalem Road Scotch Plains NJ 07076 Tel: 908-233-7240 Fax: 908-233-1354 Email: blake4xray@worldnet.att.net Web: Blake Industries will be exhibiting Huber and Blake instruments and accessories for x-ray diffraction and crystallography with sealed tube, rotating anode or synchrotron sources. Brandel # 307 8561 Atlas Drive Gaithersburg MD 20877 Tel: 800-948-6506 Fax: 301-869-5570 Email: sales@brandel.com Web: www.brandel.com Will be exhibiting their pressure-based Plate Sealing Systems for applying a uniform siliconized or adhesive seal for most any plate configuration, height and composition. Systems can be used with a variety of sealing tapes, including transparent, translucent, foils and gas permeable. Tapes are available for use with most chemicals (Including DMSO) and capable of withstanding temperatures as low as -70ĄC. Automated systems are an ideal component for integration into liquid handling/robotic systems. Models with plate stackers are available. Bruker AXS Inc. Booth #120 5465 E. Cheryl Parkway Madison, WI 53711 Tel: 608-276-3000 Fax: 608-276-3006 Email: info@bruker-axs.com Web: www.bruker-axs.com Provides advanced X-ray solutions in life sciences, chemical and materials science. Latest APEX II small molecule CCD systems feature highest sensitivity for all types of crystalline samples, including micro crystals and weak diffractors, and handle advanced research problems with twins, strong absorbers, charge density studies, modulated structures and diffuse scattering. Biological macromolecule systems feature Crystal Farm(r) growth plate imaging, sensitive, large area PROTEUM CCDs and high brilliance MICROSTAR generators for high-resolution data and high-throughput screening at home. Synchrotron CCDs feature fast readout and various sizes. Systems for combinatorial screening and SAXS highlight 2D fast readout, low noise detectors. Cambridge Crystallographic Data Centre #326,328 CCDC, 12 Union Road Cambridge CB2 1EZ United Kingdom Tel: 44-1223-336408 Fax: 44-1223-336033 Email: battle@ccdc.cam.ac.uk Web: www.ccdc.cam.ac.uk The CCDC collates and distributes the Cambridge Structural Database (CSD) which contains comprehensive crystal structure data for over 300,000 small organic and metal-organic compounds. The CSD System comprises the database itself, accompanying search and analysis software and includes the structural knowledge bases Mogul (for rapid retrieval of molecular geometry from the CSD) and IsoStar (a knowledge base of intermolecular interactions). The CCDC also undertakes the development of a range of applications software - GOLD (protein-ligand docking), Relibase+ (search and analysis of protein-ligand complexes), SuperStar (prediction of protein-ligand interactions) and DASH (crystal structure solution from powder diffraction data). CCP4 #327 Daresbury Laboratory Keckwick Lane Warrington Cheshire WA4 4AD United Kingdom Tel: 44-1925-603929 Fax: 44-1925-603825 Email: m.e.howard-eales@ccp4.ac.uk Web: www.ccp4.ac.uk The Collaborative Computational Project No. 4 (CCP4) provides a software suite for macromolecular structure determination by X-ray crystallography used by academic institutions and commercial organizations around the world. Income form the project supports maintenance, distribution and development of the software, and funds additional activities including sponsorship of educational workshops, an annual Study Weekend, hosting e-mail discussion lists, and producing a bi-annual newsletter. CCP4 staff will be available to discuss any aspect of the project, including the latest release (5.0), the CCP4 molecular graphics program, the graphical user interface (CCP4i), and the data processing package MOSFLM. Corning Incorporated # 125,127 45 Nagog Park Acton, MA 01720 Tel: 978-635-2200 Fax: 978-635-2476 Email: clswebmail@corning.com Web Site: www.corning.com/lifesciences Corning Incorporated is a diversified technology company, manufacturing high-quality, high performance consumables for the life science market. With expertise in surface chemistry, injection molding and material science, Corning offers plastic products to service the field of cell culture, liquid handling, filtration, genomics, and high throughput screening. Corning will be highlighting its 96 and 384 well protein crystallization plates Cryo Industries of America # 216 11124 S. Willow Street Manchester NH 03103 Tel: 603-621-9957 Fax: 603-621-9960 Email: cryo@cryoindustries.com Web: www.cryoindustries.com CRYO Industries has a complete (CRYOCOOL) range of Gas Stream Coolers, LHe, LN2, and Cryogen Free versions for Helium and Nitrogen. The CRYOCOOL can maintain the crystal as low as 4.5K or as high as 500K. Our Single Stream design means low gas consumption, minimizes turbulence, provides a laminar flow region in excess of 10mm, and is easy to use. DataCentric Automation and Hamiliton Corp #213 7109 Baker's Bridge Avenue Brentwood TN 37027 Tel: 615-263-9406 Fax: 615-263-9431 Email: dave.riling@dcacorp.com Web: www.dcacorp.com DataCentric Automation is a solution-based provider of laboratory automation and informatics. Our Rhombix Series of products delivers advanced automation solutions for protein crystallography experiment definition, plate preparation, storage and imaging, tightly integrated with a database that can be queried for experiment optimization. Using robotics and intelligent automation techniques, driven around a core database - the data-centric paradigm - enables disparate instrumentation to work cohesively, adapt to process changes, and use data more effectively. Delong America Inc. # 202 5775 Victoria Suite 224 Montreal Quebec H3W 2R4 Canada Tel: 514-904-1202 Fax: 763-374-0242 Email: info@delongamerica.com Web: www.dicomps.com Diamond Wire Technology #201 1605 S. Murray Blvd Colorado Springs CO 80916 Tel: 719-570-1150 Fax: 719-570-1176 Email: info@diamondwiretech.com Web: www.diamondwiretech.com Douglas Instruments #309 Westfield Farm East Garston Berkshire RG177HD United Kingdom Tel: 44-1488-649090 Fax: 44-1488-648975 Email: anne-marie@douglas.co.uk Web: www.douglas.co.uk Designs and manufactures the IMPAX 1-5 and Oryx 1-6 systems for automatic protein crystallization. Both systems are mainly designed to carry out crystallization by the microbatch method, although Oryx 1-6 can also perform crystallization by vapor diffusion. Microbatch has many advantages including greater speed - and also the fact that it is truly micro - and consequently uses less protein. Recent studies have shown that microbatch finds a comparable or (in one case) a much greater number of hits than vapor diffusion in screening experiments. The company also makes miniaturized plates especially for crystallization by both vapor diffusion and microbatch. Genomic Solutions # 111,113 4355 Varsity Drive Ann Arbor MI 48108 Tel: 734-975-4800 Fax: 734-975-4808 Email: info@genomicsolutions.com Web: www.genomicsolutions.com Automated Honeybee Protein Crystallization System: Honeybee systems are designed with components to support protein crystallization experiments. Proprietary synQUAD allows fast, non contact dispense of both mother liquor and proteins. Dispense "on the fly" or in "step and repeat mode". Honeybee Systems are designed to support Microbatch, Sitting Drop, Hanging Drop, and Combinatorial Dispense applications. Hummingbird Systems provide fast, highly parallel non contact dispensing and transfer of compounds. The proprietary Hummingbird involves sipping of sample from a source plate using narrow-bore glass capillaries. Transfer occurs by aspirating sample using capillary action followed by dispensing with a pulse of air. Hummingbird cassettes hold 96 or 384 capillaries in a format to fit standard plates Cartesian Pipettor: The Cartesian Pipettor provides non Contact dispense via air displacement technology. Transfer up to 550 uL from a deep well plate to crystal plates with a simple GUI interface. Gilson, Inc. #225,227 3000 W. Beltline Hwy Middleton WI 53562 Tel: 608-828-3252 Fax: 608-831-4451 Email: swagner@gilson.com Web: www.gilson.com A leading manufacturer of protein crystallography instrumentation for the pharmaceutical and biotechnology industries. With Gilson innovations, the process of preparing crystals is faster and easier than ever before. Gilson's 925 PC Workstation automates the preparation of protein crystallography experiments in minutes and is designed for high-throughput screening for hanging, sitting, and microbatch crystallography. This versatile workstation accepts many types of crystallography plates, including Greiner(tm), Neuro Probe(tm), Corning(tm), and Intelli-Plate. Gilson's range of systems work with 96- or standard 24-well formats, providing the ideal instruments to fit a variety of needs. Flexibility, reliability, and performance make these workstations invaluable tools for creating diffraction-quality crystals. Greiner Bio-One, Inc. # 102 1205 Sarah Street Longwood FL 32750 Tel: 407-333-2800 Fax: 407-333-3001 Email: INFO@us.gbo.com Web: www.gbo.com/bioscience Introducing the 1536 well Imp@ct(tm) Plate to facilitate high-throughput, small volume microbatch crystallography, optimizing crystal growth investigations and X-ray diffraction analyses with reduced time and cost. CrystalQuick(tm) microplates with CrystalDrop(tm) lids expand a 96 well platform to allow simultaneous sitting and hanging drop vapor diffusions. Select from a variety of well styles to enhance crystal screening. Universal 24 well ComboPlate(tm) accommodates 18 mm cover slips for hanging drops and individual well sealing. CrystalBridges(tm) enable sitting drop applications within each well. Hampton Research #115 34 Journey Aliso Viejo CA 92656 Tel: 949-425-1321 Fax: 949-425-1611 Email: info@hrmail.com Web: www.hamptonresearch.com Crystallization research tools and solutions for crystal growth. What's new? CrystalCap magnetic with 2D bar code, greased 24 and 48 well VDX plate in microplate footprints with 12 and 18 mm siliconized cover slides. Plastic circle and square cover slides, crystallization grade agarose, SaltRx crystallization screen, Fluorinert, and more. Please stop by, say hello, and check out the new stuff. Hewlett Packard # 200 200 Forest Street Marlboro MA 01752 Tel: 508-467-3030 Fax: 508-467-5836 Email: angela.loh@hp.com Web: www.hp.com/techservers HP delivers innovative, standards-based solutions running Linux and Microsoft Windows(r) including Intel(r) and AMD Opteron(tm) servers, an adaptive StorageWorks infrastructure accommodating multiple terabytes of data, 3D stereo-capable graphics workstations, and services. And by working with crystallographic software developers, HP provides a robust and well-tested environment for crystallographic computing. Innovadyne Technologies # 311 2835 Duke Court Santa Rosa CA 95407 Tel: 707-547-2500 Fax: 707-547-2501 Email: lfischer@innovadyne.com Web: www.innovadyne.com International Union of Crystallography #321 PO Box 951 Chester Cheshire CH2 2DZ United Kingdom Tel: 44-1244-376386 Fax: 44-1244-373675 Email: as@iucr.org Web: www.iucr.org The IUCr is delighted to announce the imminent arrival of Acta Crystallographica Section F: Structural Biology and Crystallization Communications, an all-electronic journal for the rapid publication of structural genomics, protein structure and crystallization results. Visit the IUCr stand to find out more. Kluwer Academic Publishers #324 101 Philip Drive Norwell, MA 02061 Tel: 781-871-6600 Fax: 781-871-6528 Email: jfoster@wkap.com Web: Kluwer Academic Publishers' Crystallography Program-featuring the International Tables for Crystallography (co-published with the IUCr)...Volume A - Space-group symmetry, Brief teaching edition of Volume A; Volume B - Reciprocal space; Volume C - Mathematical, physical and chemical tables, Third Edition; Volume D - Physical properties of crystals; Volume E - Subperiodic groups; Volume F - Crystallography of biological macromolecules. Kluwer is also the proud publisher of the Journal of Chemical Crystallography and Structural Chemistry. Visit the booth for a free sample journal and a conference discount off of texts like Lewars' Computational Chemistry and our 2004 essential major reference works. MAR USA, Inc. # 320 1880 Oak Avenue Evanston IL 60201 Tel: 847-869-1548 Fax: 847-869-1587 Email: info@mar-usa.com Web: www.mar-usa.com Mar USA develops, manufactures, and markets imaging detector systems for X-ray diffraction applications: the Mar345 Imaging Plate system, the 165 mm diameter Marccd, and three Marmosaic ccd-based detectors (225, 300, and 325 mm). These systems have set the standard at synchrotrons for high performance - highest data quality, high speed, ease of use and ultra reliability. The highly automated Mardtb goniostat is now available with the Marcsc accessory. This cryogenic sample changer automatically mounts and safely retrieves samples under computer control. The combination of a Marmosaic detector and Mardtb goniostat with the cryogenic sample changer provides a reliable and remarkably affordable synchrotron end station for protein crystallography. A Mar345 scanner or Marccd, combined with the Mardtb and Marcsc, is the ideal complimentary screening station for the home lab. MicroCal LLC # 208 22 Industrial Drive East Northampton MA 01060 Tel: 413-586-7720 Fax: 413-586-0149 Email: info@microcalorimetry.com Web: www.microcalorimetry.com MicroCal manufactures ultrasensitive VP-Isothermal Titration and Differential Scanning Calorimeters which are capable of rapidly characterizing binding and structural properties of biomolecules in highly automated, easy-to-perform experiments. The VP series represents major advances in sensitivity, reproducibility and stability, which translates into smaller sample requirements and greater precision. Molecular Dimensions, Inc. #315 P.O. Box 1001 Apopka FL 32704 Tel: 407-866-6901 Fax: 407-869-4444 Email: tony@moleculardimensions.com Web: www.moleculardimensions.com Supplies innovative protein crystal growth screens developed within our customers' laboratories as well as plates cover slides, and protein expression media including SeMet. Molecular Dimensions sells the only cooled incubators specifically designed for crystal growth. With " 0.5Ą C accuracy from 0 - 50Ą C these incubators operate virtually vibration free. Now a new bench top, stackable model is available to compliment the popular 6.36, 8.83 & 13.77 cubic foot range. At ACA 2004 Molecular Dimensions will exhibit mosquito the ideal liquid handling tool for setting up protein crystallization drops in high throughput screening plates. Nextal Biotechnologies #313 1751 Richardson, S. 6101 Montreal Quebec H3K 1G6 Canada Tel: 514-849-8057 Fax: 514-849-4588 Email: rmndiaye@nextalbiotech.com Web: www.nextalbiotech.com Provides products designed specifically for the experimental needs of protein crystallization. Our innovative plates have independent screwable crystallization supports that are grease free, facilitating new experimental strategies. New, Nextal is also offering the first all-in-one pre-filled crystallization plate. We provide you with a fast and easy set-up; fresh conditions every time and increased reproducibility. Protein is all you need! Osmic, Inc. #212 1900 Taylor Road Auburn Hills MI 48326 Tel: 248-232-6400 Fax: 284-232-6500 Email: arlene.pollock@osmic.com Web: www.osmic.com Come see what's new from the pioneer and leading developer of multilayer x-ray optic technology. Osmic offers a full line of standard and custom design products, from optics to source-optic beam modules, designed for single-crystal, small angle x-ray scattering, x-ray reflectivity, x-ray diffraction, wavelength dispersive spectroscopy, micro x-ray diffraction, micro x-ray fluorescence, and more x-ray analytical techniques. Our latest and patented VariMax(tm) line of optics offer the highest flux, a well defined beam (both spatially and spectrally), and adjustable divergence for unmatched data quality and excellent resolution capabilities for protein crystallography. Integrated micro-focusing source and specially designed multilayer optic beam modules offer rotating anode like performance and are the ultimate in sealed tube x-ray source technology. Our expert staff and application driven approach to product development enable us to provide the best optics and instrumentation for a broad spectrum of x-ray analytical techniques Oxford Cryosystems #116 7 Jackson Road Devens MA 01432 Tel: 978-772-7930 Fax: 978-772-7945 Email: liz@oxfordcryosystems.com Web: www.oxfordcryosystems.com Oxford Cryosystems started manufacturing the original Cryostream Cooler in 1985 but still leads the field in cryostat design. This year we are launching the Cobra - our new NON-LIQUID Cryostream with a temperature range of 80-500 K and a fast cooldown time of 30 minutes. The Cobra will compliment our Cryostream range including the 700 series & the Cryostream Plus. The company also produces the HeliX, an open flow helium cryostat and the Phenix, a revolutionary 11K helium cryostat for powder diffraction. Other products include the Metripol, a birefringence imaging system, Cryoaccessories and a software suite, Crystallographica, incorporating Crystallographica Search Match (CSM), both of which can be downloaded for free trial periods at www.crystallographica.com Oxford Cryosystems #116 7 Jackson Road Devens MA 01432 Tel: 978-772-7930 Fax: 978-772-7945 Email: liz@oxfordcryosystems.com Web: www.oxfordcryosystems.com Started manufacturing the original Cryostream Cooler in 1985 but still leads the field in cryostat design. This year we integrated the Cryoshutter, and innovative stream deflector for flash freezing and annealing, into the 700 series. The company also produces the HeliX, an open flow cryostat, using helium gas to reach temperatures as low as 28K and the Phenix, a revolutionary 11K helium cryostat for powder diffraction. Other products include the Metripol, a birefringence imaging system for quantifying strain and/or order in samples. Cryoaccessories and a software suite, Crystallographica, incorporating Crystallographica Search Match (CSM), both of which can be downloaded for free trial periods at www.crystallographica.com Oxford Diffraction #100 130 A Baker Avenue Extension Concord MA 01754 Tel: 978-371-5506 Fax: 978-369-8287 Email: info@oxford-diffraction.com Web: www.oxford-diffraction.com Designs and manufactures chemical and protein single crystal X-ray diffraction equipment. Our superior products include the newly launched 'Xcalibur 3' featuring the direct taper 'Sapphire 3' CCD detector, the revolutionary protein diffractometer 'Xcalibur PX Ultra' and the patented 'Helijet' open flow helium jet. 'Xcalibur PX Ultra' features a four circle kappa goniometer, the revolutionary 'Enhance Ultra' X-ray source; which provides comparable X-ray intensity to a 5 kW rotating anode fitted with multi-graded Confocal optics from a 2.2 kW sealed tube and the patented 165 mm large area 'Onyx' CCD detector. Precision Detectors #206 34 Williams Way P.O. Box 738 Bellingham MA 02019 Tel: 508-966-3847 Fax: 508-966-3758 Email: info@precisiondetectors.com Web: www.precisiondetectors.com Dynamic light scattering for protein purity. RCSB Protein Data Bank #323 Department of Chemistry, Rutgers University 610 Taylor Road Piscataway NJ 08854 Tel: 732-445-0103 Fax: 732-445-4320 Email: info@rcsb.org Web: www.pdb.org The Protein Data Bank is the single worldwide repository for the processing and distribution of 3-D biological macromolecular structure data. Rigaku #204 9009 New Trails Drive The Woodlands TX 77381 Tel: 281-363-1033 Fax: 281-364-3628 Email: sld@rigakumsc.com Web: www.rigakumsc.com Redefining the home lab as the world's leading resource for single-crystal X-ray diffraction hardware, software and contract services. Rigaku/MSC offers fully integrated small and macromolecule applications, Rigaku generators, X-ray optical systems, cryo-cooling devices and peripheral devices. In addition, Rigaku/MSC provides small and macromolecular structure determination services on a contract basis. RoboDesign International #204 5920 Pasteur Court Carlsbad CA 92008 Tel: 760-438-5282 Fax: 760-438-5286 Email: blyons@robodesign.com Web: www.robodesign.com RoboDesign International, Inc. offers several new products this year with its CrystalMation(tm) product line. The first is a fully integrated and automated 1,000 plate high-throughput crystallization platform, including screen making, protein dispense modules, plate handling, incubation, and inspection with automated scoring, data mining, and optimization software. The second is our modular high-speed 2,500 - 10,000 plate crystallization storage, retrieval and inspection system for use in cold rooms. The third, for smaller labs, is the Minstrel I(tm), with options for fully automated plate handling, storage and inspection of 60 - 80 plates. Of course, "Sweet Image(tm)" image-enhancement software is available for all RoboDesign systems. Shamrock Stuctures LLC #301 1440 Davey Road Woodridge IL 60517 Tel: 630-739-3215 Fax: 630-739-1753 Email: jmiller@shamrockstructures.com Web: www.shamrockstructures.com Southeast Regional Collaborative Access Team (SER-CAT) #325 University of Georgia, Biochemistry & Molecular Biology B202A Life Sciences Bldg. Athens GA 30602 Tel: 706-542-3384 Fax: 706-542-3077 Email: lhoranyi@uga.edu Web: www.ser-cat.org The Southeast Regional Collaborative Access Team (SER-CAT) was formed in 1997 by 22 participating institutions to provide third generation X-ray capabilities to macromolecular crystallographers and structural biologists in the Southeast and Midwest. Its facilities, which are nearly complete, are located at Sector 22 of the Advanced Photon Source of the Argonne National Laboratory and consist of both an ID and a BM beamline. SER-CAT's primary interest is serving its membership with the most advanced data collection facilities for macromolecular crystallography. Membership information is available at www.ser-cat.org. Tecan #303 4022 Stirrup Creek Drive, Suite 310 Durham NC 27703 Tel: 919-361-5200 Fax: 919-361-5200 Email: michelevalenta@tecan.com Web: www.tecan.com A leading provider of world-class automated liquid handling and laboratory robotic systems for over 23 years offers the Protein Crystallization Workstation (PCW), a fully automated solution for high performance protein crystal growth and screening studies. Automated applications include custom buffer creation and highly parallel set-up of sitting drop, hanging drop (new!) and microbatch experiments. Features such as low-vibration incubators, dynamic anti-evaporation cover and a high-precision liquid handling arm help insure high-quality crystal formation. Integrated image capture and analysis systems enable real-time monitoring of crystal growth. User-friendly software allows simplified experimental set-up, with novel CrysTool converter for creation of multi-parametric worklists. TriTek Corp #317 5263 Stewart Road Sumerduck VA 22742 Tel: 540-439-3690 Fax: 540-439-4009 Email: angie@tritekcorp.com Web: www.tritekcorp.com CrystalPro is a fully integrated, computer controlled, high throughput, variable zoom microscopy system designed for detecting tiny crystals in large fields of view. Unique software enables the CrystalPro to auto-scan each well while capturing images, with annotation and time/date stamp, at a rate of 768 wells per hour. Customized program options include crystal discrimination and image analysis. Veeco Instruments # 214 100 Sunnyside Blvd Woodbury NY 11797 Tel: 516-677-0200 Fax: 516-677-0248 Email: daxelrod@veeco.com Web: www.veeco.com Large-scale protein crystallization efforts require fast, reliable screening of thousands of potentially crystal-producing experiments. The OASIS 1750 automatically locates, characterizes and scores protein crystal growth, providing rapid inspection of more than 8000 wells per hour. High-speed auto-focus and patent-pending illumination ensure reliable crystal detection and classification. Wyatt Technology Corp. # 305 6300 Hollister Avenue Santa Barbara CA 93117 Tel: 805-681-9009 Fax: 805-681-0123 Email: info@wyatt.com Web: www.wyatt.com Light Scattering for the Masses! Wyatt Technology is the world leader in the design and manufacture of multi-angle light scattering systems for absolute protein characterization. The DAWN and miniDAWN instruments may be used as on-line detectors for oligomerization investigations and analyses, while the WyattQELS can be added to study protein purity and aggregation. The Eclipse protein separation system can be used to separate proteins without the molecules interacting with the stationary phase. Finally, Wyatt's ASTRA software can determine absolute masses and sizes of proteins, determine A2 for helping to predict protein crystallization conditions. The software can also be used for determining the degree of glycosylation and PEGylation of a protein sample. Xenocs SA #300 19 Rue F. Blumet Sassenage F38360 France Tel: 33-4-7626-9540 Fax: 33-4-7626-9549 Email: sales@xenocs.com Web: www.xenocs.com Xenocs manufactures multilayer-coated optics. Key functions include simultaneous monochromatization and focusing/collimation required for various applications including: Single crystal diffraction, protein crystallography, X-RAY Reflectometry, Wavelength Dispersive X-RAY fluorescence, Electron Probe Micro Analysis, Micro diffraction, X-RAY / EUV spectroscopy & imaging, X-RAY astronomy, Neutron guide and polarization. You can rely on more than 10 years experience in thin film deposition and characterization down to few nanometers resolution. We deliver solutions to OEMs and end users from early stage of conception up to finished goods.