Department of Biopharmaceutical Sciences

College of Pharmacy
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Wang Ying Xiaoyu Science Magazine

Wang&Team

Professor Z. Jim Wang (center), together with Dr. Ying He, postdoctoral fellow (left) and Xiaoyu Hu, graduate student (right) are co-authors of a cover article in the September 20, 2013 Science, titled "Constitutive µ-opioid receptor activity leads to long-term endogenous analgesia and dependence."
The work of the UIC team involved a novel hypothesis to determine acute and chronic pain, and identified internal mechanisms of long-term pain relief. This work was based on Dr. Wang’s original discovery of constitutive µ-opioid receptor activity, made during his doctoral research at the University of California San Francisco.

Corder G, Doolen S, R. R. Donahue, Winter M, Jutras B, He Y, X. Hu, J.S. Wieskopf,
J.S. Mogil, D.R. Storm, Z.J. Wang, K.E. McCarson, and B.K. Taylor. Constitutive µ-opioid receptor activity leads to long-term endogenous analgesia and dependence. Science; 2013: Vol. 341 (6152); 1394-99 . DOI: 10.1126/science.1239403. http://www.sciencemag.org/content/341/6152/1394


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