Seungpyo Hong, Ph.D.
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Assistant Professor, Pharmaceutics and Bioengineering
Contact Information 833 South Wood Street 355 PHARM, MC 865 Chicago, IL 60612-7231 Office: (312) 413-8294 Fax: (312) 996-0098 Email: sphong@uic.edu Lab Website |
Education
Postdoctoral - Massachusetts Institute of Technology - 2008
Ph.D. - University of Michigan - 2006
M.S. - Hanyang University/Korea Institute of Science and Technology - 2001
B.S. - Hanyang University - 1999
Research Interests
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Targeted Drug Delivery Using Polymeric Nanomaterials
(Related Publications) |
Capturing Devices for Specific Target Cells
(Related Publications) |
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Nano-scale Polymer-Cell Interactions
(Related Publications) |
Fundamental Polymer Science
(Related Publications) |
Publications (2004-2009)
Jin SE, Bae JW, Hong S. Multiscale observation of biological interactions of nanocarriers: From nano to macro. Microsc Res Tech. 2010 Mar 15. [Epub ahead of print] DOI
Myung JH, Launiere CA, Eddington DT, Hong S. Enhanced Tumor Cell Isolation by a Biomimetic Combination of E-selectin and anti-EpCAM: Implications for the Effective Separation of Circulating Tumor Cells (CTCs). Langmuir, 2010 Feb 16. [Epub ahead of print] DOI
Hong S, Rattan R, Majoros IJ, Mullen DG, Peters JL, Shi X, Bielinska AU, Blanco L, Orr BG, Baker JR, and Banaszak Holl MM, The Role of Gaglioside GM1 in Cellular Internalization Mechanisms of Poly(amidoamine) Dendrimers Bioconjugate Chemistry 2009, In press.
Chen J, Hessler JA, Putchakayala K, Panama BK, Khan DP, Hong S, Mullen DG, DiMaggio SC, Som A, Tew GN, Lopatin AN, Baker JR, Banaszak Holl MM, and Orr BG, Cationic Nanoparticles Induce Nanoscale Disruption in Living Cell Plasma Membranes, Journal of Physical Chemistry B 2009, In press.
Kim Y, Han SI, Hong S. Effect of modified carbon nanotube on the properties of aromatic polyester nanocomposites. Polymer. 2008;49(15):3335-45. DOI
Landmark KJ, DiMaggio S, Ward J, Vogt S, Hong S, Kotlyar A, Penner-Hahn JE, Baker JR, Banaszak Holl MM, Orr BG. Synthesis, Characterization, and In Vitro Testing of Superparamagnetic Iron Oxide Nanoparticles Targeted Using Folic Acid-Conjugated Dendrimers. ACS Nano. 2008; 2(4): 773-783. DOI
Karnik R, Hong S, Zhang HM, Y, Anderson DK, JM, Langer R. Nanomechanical Control of Cell Rolling in Two Dimensions through Surface Patterning of Receptors. Nano Letters. 2008; 8(4): 1153-1158. DOI
Mahdavi A, Ferreira L, Sundback C, Nichol JW, Chan EP, Carter DJD, Bettinger CJ, Patanavanich S, Chignozha L, Ben-Joseph E, Galakatos A, Pryor H, Pomerantseva I, Masiakos PT, Faquin W, Zumbuehl A, Hong S, Borenstein J, Vacanti J, Langer R, Karp JM. A biodegradable and biocompatible gecko-inspired tissue adhesive. Proceedings of the National Academy of Sciences of the United States of America 2008;105 (7):2307-12. DOI
Karp JM, Mahdavi A, Hong S, Khademhosseini A, Langer R. Microscale Approaches for Bone Tissue Engineering. In: Khademhosseini A, Borenstein J, Takayama S, Toner M, editors. Micro and Nanoengineering of the Cell Microenvironment: Technologies and Applications. Norwood, MA: Artech House, Inc., 2008.
Peer D*, Karp JM*, Hong S*, FaroKhzad OC, Margalit R, Langer R. Nanocarriers as an emerging platform for cancer therapy. Nature Nanotechnology 2007;2(12): 751-60. *co-first authors
Nam YW, Kim WN, Cho YH, Chae DW, Kim GH, Hong S, Hwang SS, Hong SM. Morphology and Physical Properties of Binary Blend Based on PVDF and Multi-Walled Carbon Nanotube. Macromolecular Symposia 2007;249-250:478-84. DOI
Leroueil PR, Hong S, Mecke A, Baker JR, Orr BG, Banaszak Holl MM. Nanoparticle interaction with biological membranes: Does nanotechnology present a janus face? Accounts of Chemical Research 2007;40 (5):335-42. DOI
Hong S, Mecke A, Leroueil PR, Banaszak Holl MM, Orr BG. Dendrimer-Bilayer Interactions. In: Majoros I, Baker J, editors. Dendrimer Based Nanomedicine. Hackensack, NJ: World Scientific Publishing, 2007.
Hong S, Leroueil PR, Majoros IJ, Orr BG, Baker JR, Banaszak Holl MM. The binding avidity of a nanoparticle-based multivalent targeted drug delivery platform. Chemistry & Biology 2007;14 (1):107-15. DOI
Hong S, Lee D, Zhang H, Zhang JQ, Resvick JN, Khademhosseini A, King MR, Langer R, Karp JM. Covalent immobilization of P-selectin enhances cell rolling. Langmuir 2007;23:12261-8. DOI
Gu FX, Karnik R, Wang AZ, Alexis F, Levy-Nissenbaum E, Hong S, Langer RS, Farokhzad OC. Targeted nanoparticles for cancer therapy. Nano Today 2007;2 (3):14-21. DOI
Chae DW, Hwang SS, Hong SM, Hong S, Cho BG, Kim BC. Influence of high contents of silver nanoparticles on the physical properties of poly(vinylidene fluoride). Molecular Crystals and Liquid Crystals 2007;464:815-23. DOI
Shi X, Bi X, Ganser TR, Hong S, Myc LA, Desai A, Banaszak Holl MM, Baker JR. HPLC analysis of functionalized poly(amidoamine) dendrimers and the interaction between a folate-dendrimer conjugate and folate binding protein. Analyst 2006;131 (7):842-8. DOI
Hong S, Leroueil PR, Janus EK, Peters JL, Kober MM, Islam MT, Orr BG, Baker JR, Banaszak Holl MM. Interaction of polycationic polymers with supported lipid bilayers and cells: Nanoscale hole formation and enhanced membrane permeability. Bioconjugate Chemistry 2006;17 (3):728-34. DOI
Hong S, Hessler JA, Banaszak Holl MM, Leroueil PR, Mecke A, Orr BG. Physical Interactions of Nanoparticles with Biological Membranes: The Observation of Nanoscale Hole Formation. Journal of Chemical Health & Safety 2006;13 (3):16-20. DOI
Hong S, Gil YS, Hwang SS, Hong SM. Effect of poly(esterimide)s as compatibilizers on the physical properties of poly(etherimide)/thermotropic liquid crystalline polymer in-situ composites. Polymer Journal 2004;36 (4):271-83. DOI
Hong S, Bielinska AU, Mecke A, Keszler B, Beals JL, Shi XY, Balogh L, Orr BG, Baker JR, Banaszak Holl MM. Interaction of poly(amidoamine) dendrimers with supported lipid bilayers and cells: Hole formation and the relation to transport. Bioconjugate Chemistry 2004;15 (4):774-82. DOI