Seungpyo Hong, Ph.D.
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Assistant Professor of Pharmaceutics Contact Information |
Education
- Postdoctoral - Massachusetts Institute of Technology - 2008
- Ph.D. - University of Michigan - 2006
- M.S. - Hanyang University/Korea Institute of Science and Technology - 2001
- B.S. - Hanyang University - 1999
Research Interests
- Targeted Drug Delivery using Polymeric Nanomaterials
- Capturing Devices for Specific Target Cells
- Nano-scale Polymer-Cell Interactions
Publications (2004-2009)
- S. Hong, R. Rattan, I.J, Majoros, D.G. Mullen, J.L. Peters, X. Shi, A.U. Bielinska, L. Blanco, B.G. Orr, J.R. Baker, and M.M. Banaszak Holl, “The Role of Gaglioside GM1 in Cellular Internalization Mechanisms of Poly(amidoamine) Dendrimers” Bioconjugate Chemistry 2009, In press.
- J. Chen, J.A. Hessler, K. Putchakayala, B.K. Panama, D.P. Khan, S. Hong, D.G. Mullen, S.C. DiMaggio, A. Som, G.N. Tew, A.N. Lopatin, J.R. Baker, M.M. Banaszak Holl, and B.G. Orr , “Cationic Nanoparticles Induce Nanoscale Disruption in Living Cell Plasma Membranes”, Journal of Physical Chemistry B 2009, In press.
- Kim Y, Han SI, Hong S. Effect of modified carbon nanotube on the properties of aromatic polyester nanocomposites. Polymer. 2008;49(15):3335-45.
- Landmark KJ, DiMaggio S, Ward J, Vogt S, Hong S,
Kotlyar A, Penner-Hahn JE, Baker JR, Banaszak Holl MM, Orr BG. Synthesis, Characterization, and In Vitro Testing of Superparamagnetic Iron Oxide Nanoparticles Targeted Using Folic Acid-Conjugated Dendrimers. ACS Nano. 2008; 2(4): 773-783.
- Karnik R, Hong S, Zhang HM, Y, Anderson DK, JM, Langer R. Nanomechanical Control of Cell Rolling in Two Dimensions through Surface Patterning of Receptors. Nano Letters. 2008; 8(4): 1153-1158.
- Mahdavi A, Ferreira L, Sundback C, Nichol JW, Chan EP, Carter DJD, Bettinger CJ, Patanavanich S, Chignozha L, Ben-Joseph E, Galakatos A, Pryor H, Pomerantseva I, Masiakos PT, Faquin W, Zumbuehl A, Hong S, Borenstein J, Vacanti J, Langer R, Karp JM. A biodegradable and biocompatible gecko-inspired tissue adhesive. Proceedings of the National Academy of Sciences of the United States of America 2008;105 (7):2307-12.
- Karp JM, Mahdavi A, Hong S, Khademhosseini A, Langer R. Microscale Approaches for Bone Tissue Engineering. In: Khademhosseini A, Borenstein J, Takayama S, Toner M, editors. Micro- and Nanoengineering of the Cell Microenvironment: Technologies and Applications. Norwood, MA: Artech House, Inc., 2008.
- Peer D*, Karp JM*, Hong S*, FaroKhzad OC, Margalit R, Langer R. Nanocarriers as an emerging platform for cancer therapy. Nature Nanotechnology 2007;2(12): 751-60. *co-first authors
- Nam YW, Kim WN, Cho YH, Chae DW, Kim GH, Hong S, Hwang SS, Hong SM. Morphology and Physical Properties of Binary Blend Based on PVDF and Multi-Walled Carbon Nanotube. Macromolecular Symposia 2007;249-250:478-84.
- Leroueil PR, Hong S, Mecke A, Baker JR, Orr BG, Banaszak Holl MM. Nanoparticle interaction with biological membranes: Does nanotechnology present a janus face? Accounts of Chemical Research 2007;40 (5):335-42.
- Hong S, Mecke A, Leroueil PR, Banaszak Holl MM, Orr BG. Dendrimer-Bilayer Interactions. In: Majoros I, Baker J, editors. Dendrimer Based Nanomedicine. Hackensack, NJ: World Scientific Publishing, 2007.
- Hong S, Leroueil PR, Majoros IJ, Orr BG, Baker JR, Banaszak Holl MM. The binding avidity of a nanoparticle-based multivalent targeted drug delivery platform. Chemistry & Biology 2007;14 (1):107-15.
- Hong S, Lee D, Zhang H, Zhang JQ, Resvick JN, Khademhosseini A, King MR, Langer R, Karp JM. Covalent immobilization of P-selectin enhances cell rolling. Langmuir 2007;23:12261-8.
- Gu FX, Karnik R, Wang AZ, Alexis F, Levy-Nissenbaum E, Hong S, Langer RS, Farokhzad OC. Targeted nanoparticles for cancer therapy. Nano Today 2007;2 (3):14-21.
- Chae DW, Hwang SS, Hong SM, Hong S, Cho BG, Kim BC. Influence of high contents of silver nanoparticles on the physical properties of poly(vinylidene fluoride). Molecular Crystals and Liquid Crystals 2007;464:815-23.
- Shi X, Bi X, Ganser TR, Hong S, Myc LA, Desai A, Banaszak Holl MM, Baker JR. HPLC analysis of functionalized poly(amidoamine) dendrimers and the interaction between a folate-dendrimer conjugate and folate binding protein. Analyst 2006;131 (7):842-8.
- Hong S, Leroueil PR, Janus EK, Peters JL, Kober MM, Islam MT, Orr BG, Baker JR, Banaszak Holl MM. Interaction of polycationic polymers with supported lipid bilayers and cells: Nanoscale hole formation and enhanced membrane permeability. Bioconjugate Chemistry 2006;17 (3):728-34.
- Hong S, Hessler JA, Banaszak Holl MM, Leroueil PR, Mecke A, Orr BG. Physical Interactions of Nanoparticles with Biological Membranes: The Observation of Nanoscale Hole Formation. Journal of Chemical Health & Safety 2006;13 (3):16-20.
- Hong S, Gil YS, Hwang SS, Hong SM. Effect of poly(esterimide)s as compatibilizers on the physical properties of poly(etherimide)/thermotropic liquid crystalline polymer in-situ composites. Polymer Journal 2004;36 (4):271-83.
- Hong S, Bielinska AU, Mecke A, Keszler B, Beals JL, Shi XY, Balogh L, Orr BG, Baker JR, Banaszak Holl MM. Interaction of poly(amidoamine) dendrimers with supported lipid bilayers and cells: Hole formation and the relation to transport. Bioconjugate Chemistry 2004;15 (4):774-82.