Seungpyo Hong, Ph.D.
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Assistant Professor, Pharmaceutics and Bioengineering
Contact Information 833 South Wood Street 355 PHARM, MC 865 Chicago, IL 60612-7231 Office: (312) 413-8294 Fax: (312) 996-0098 Email: sphong@uic.edu Lab Website |
Education
Postdoctoral - Massachusetts Institute of Technology - 2008
Ph.D. - University of Michigan - 2006
M.S. - Hanyang University/Korea Institute of Science and Technology - 2001
B.S. - Hanyang University - 1999
Research Interests
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Targeted Drug Delivery Using Polymeric Nanomaterials
(Related Publications) |
Capturing Devices for Specific Target Cells
(Related Publications) |
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Nano-scale Polymer-Cell Interactions
(Related Publications) |
Fundamental Polymer Science
(Related Publications) |
Publications (2007-2012)
S. Sunoqrot, J.W. Bae, R.M. Pearson, K. Shyu, Y. Liu, D.H. Kim, and S. Hong, “Temporal Control over Cellular Targeting through Hybridization of Folate-targeted Dendrimers and PEG-PLA Nanoparticles" Biomacromolecules 2012, an ASAP article.
C.A. Launiere, M. Gaskill, G. Czaplewski, J.H. Myung, S. Hong, and D.T. Eddington, "Channel Surface Patterning of Alternating Biomimetic Protein Combinations for Enhanced Microfluidic Tumor Cell Isolation" Analytical Chemistry 2012, In press.
J.H. Myung, K.A. Gajjar, J. Saric, D.T. Eddington, and S. Hong, "Dendrimer-mediated Multivalent Binding for Enhanced Capture of Tumor Cells" Angewandte Chemie International Edition 2011, 50(49), 11769-11772.
J.W. Bae*, R.M. Pearson*, N. Patra, S. Sunoqrot, L. Vukovi, P. Kral, and S. Hong, "Dendron-mediated Self-assembly of Highly PEGylated Block Copolymers: A Modular Nanocarrier Platform" Chemical Communications 2011, 47(37), 10302-10304. *denotes co-first authors.
S. Sunoqrot, J.W. Bae, S.E. Jin, R.M. Pearson, Y. Liu, and S. Hong, "Kinetically Controlled Cellular Interactions of Polymer-Polymer and Polymer-Liposome Nanohybrid Systems" Bioconjugate Chemistry 2011, 22(3), 466-474.
H. Shen, S. Hong, R.K. Prud'homme, and Y. Liu, "Self-Assembling Process of Flash Nanoprecipitation in a Multi-inlet Vortex Mixer (MIVM) to Produce Drug-Loaded Polymeric Nanoparticles" Journal of Nanoparticle Research 2011, 13(9), 4109-4120.
C.A. Launiere, G.J. Czaplewski, J.H. Myung, S. Hong, and D.T. Eddington, "Rheologically Biomimetic Cell Suspensions for Decreased Cell Settling in Microfluidic Devices" Biomedical Microdevices 2011, 13(3), 549-557.
J.H. Myung, K.A. Gajjar, R.M. Pearson, C.A. Launiere, D.T. Eddington, and S. Hong, "Direct Measurements on CD24-Mediated Rolling of Human Breast Cancer MCF-7 Cells on E-selectin" Analytical Chemistry 2011, 83(3), 1078-1083.
Jin SE, Bae JW, Hong S. Multiscale observation of biological interactions of nanocarriers: From nano to macro. Microsc Res Tech. 2010 Mar 15. [Epub ahead of print] DOI
Myung JH, Launiere CA, Eddington DT, Hong S. Enhanced Tumor Cell Isolation by a Biomimetic Combination of E-selectin and anti-EpCAM: Implications for the Effective Separation of Circulating Tumor Cells (CTCs). Langmuir, 2010 Feb 16. [Epub ahead of print] DOI
Hong S, Rattan R, Majoros IJ, Mullen DG, Peters JL, Shi X, Bielinska AU, Blanco L, Orr BG, Baker JR, and Banaszak Holl MM, The Role of Ganglioside GM1 in Cellular Internalization Mechanisms of Poly(amidoamine) Dendrimers Bioconjugate Chemistry, 2009 August 19; 20(8); 1503-13. .
Chen J, Hessler JA, Putchakayala K, Panama BK, Khan DP, Hong S, Mullen DG, DiMaggio SC, Som A, Tew GN, Lopatin AN, Baker JR, Banaszak Holl MM, and Orr BG, Cationic Nanoparticles Induce Nanoscale Disruption in Living Cell Plasma Membranes, Journal of Physical Chemistry B, 2009; 113(32); 11179-85.
Kim Y, Han SI, Hong S. Effect of modified carbon nanotube on the properties of aromatic polyester nanocomposites. Polymer. 2008;49(15):3335-45. DOI
Landmark KJ, DiMaggio S, Ward J, Vogt S, Hong S, Kotlyar A, Penner-Hahn JE, Baker JR, Banaszak Holl MM, Orr BG. Synthesis, Characterization, and In Vitro Testing of Superparamagnetic Iron Oxide Nanoparticles Targeted Using Folic Acid-Conjugated Dendrimers. ACS Nano. 2008; 2(4): 773-783. DOI
Karnik R, Hong S, Zhang HM, Y, Anderson DK, JM, Langer R. Nanomechanical Control of Cell Rolling in Two Dimensions through Surface Patterning of Receptors. Nano Letters. 2008; 8(4): 1153-1158. DOI
Mahdavi A, Ferreira L, Sundback C, Nichol JW, Chan EP, Carter DJD, Bettinger CJ, Patanavanich S, Chignozha L, Ben-Joseph E, Galakatos A, Pryor H, Pomerantseva I, Masiakos PT, Faquin W, Zumbuehl A, Hong S, Borenstein J, Vacanti J, Langer R, Karp JM. A biodegradable and biocompatible gecko-inspired tissue adhesive. Proceedings of the National Academy of Sciences of the United States of America 2008;105 (7):2307-12. DOI
Karp JM, Mahdavi A, Hong S, Khademhosseini A, Langer R. Microscale Approaches for Bone Tissue Engineering. In: Khademhosseini A, Borenstein J, Takayama S, Toner M, editors. Micro and Nanoengineering of the Cell Microenvironment: Technologies and Applications. Norwood, MA: Artech House, Inc., 2008.
Peer D*, Karp JM*, Hong S*, FaroKhzad OC, Margalit R, Langer R. Nanocarriers as an emerging platform for cancer therapy. Nature Nanotechnology 2007;2(12): 751-60. *co-first authors
Nam YW, Kim WN, Cho YH, Chae DW, Kim GH, Hong S, Hwang SS, Hong SM. Morphology and Physical Properties of Binary Blend Based on PVDF and Multi-Walled Carbon Nanotube. Macromolecular Symposia 2007;249-250:478-84. DOI
Leroueil PR, Hong S, Mecke A, Baker JR, Orr BG, Banaszak Holl MM. Nanoparticle interaction with biological membranes: Does nanotechnology present a janus face? Accounts of Chemical Research 2007;40 (5):335-42. DOI
Hong S, Mecke A, Leroueil PR, Banaszak Holl MM, Orr BG. Dendrimer-Bilayer Interactions. In: Majoros I, Baker J, editors. Dendrimer Based Nanomedicine. Hackensack, NJ: World Scientific Publishing, 2007.
Hong S, Leroueil PR, Majoros IJ, Orr BG, Baker JR, Banaszak Holl MM. The binding avidity of a nanoparticle-based multivalent targeted drug delivery platform. Chemistry & Biology 2007;14 (1):107-15. DOI
Hong S, Lee D, Zhang H, Zhang JQ, Resvick JN, Khademhosseini A, King MR, Langer R, Karp JM. Covalent immobilization of P-selectin enhances cell rolling. Langmuir 2007;23:12261-8. DOI
Gu FX, Karnik R, Wang AZ, Alexis F, Levy-Nissenbaum E, Hong S, Langer RS, Farokhzad OC. Targeted nanoparticles for cancer therapy. Nano Today 2007;2 (3):14-21. DOI
Chae DW, Hwang SS, Hong SM, Hong S, Cho BG, Kim BC. Influence of high contents of silver nanoparticles on the physical properties of poly(vinylidene fluoride). Molecular Crystals and Liquid Crystals 2007;464:815-23. DOI