Department of Biopharmaceutical Sciences

College of Pharmacy

Seungpyo Hong, Ph.D.

Seungpyo Hong, Ph.D.

Assistant Professor, Pharmaceutics and Bioengineering

Contact Information
833 South Wood Street
355 PHARM, MC 865
Chicago, IL 60612-7231
Office: (312) 413-8294
Fax: (312) 996-0098
Lab Website

Publications (2004-2009)
Nano-scale Polymer-Cell Interactions

Jin SE, Bae JW, Hong S. Multiscale observation of biological interactions of nanocarriers: From nano to macro. Microsc Res Tech. 2010 Mar 15. [Epub ahead of print] DOI

Hong S, Rattan R, Majoros IJ, Mullen DG, Peters JL, Shi X, Bielinska AU, Blanco L, Orr BG, Baker JR, and Banaszak Holl MM, The Role of Gaglioside GM1 in Cellular Internalization Mechanisms of Poly(amidoamine) Dendrimers Bioconjugate Chemistry 2009, In press.

Chen J, Hessler JA, Putchakayala K, Panama BK, Khan DP, Hong S, Mullen DG, DiMaggio SC, Som A, Tew GN, Lopatin AN, Baker JR, Banaszak Holl MM, and Orr BG, Cationic Nanoparticles Induce Nanoscale Disruption in Living Cell Plasma Membranes, Journal of Physical Chemistry B 2009, In press.

Leroueil PR, Hong S, Mecke A, Baker JR, Orr BG, Banaszak Holl MM. Nanoparticle interaction with biological membranes: Does nanotechnology present a janus face? Accounts of Chemical Research 2007;40 (5):335-42. DOI

Hong S, Mecke A, Leroueil PR, Banaszak Holl MM, Orr BG. Dendrimer-Bilayer Interactions. In: Majoros I, Baker J, editors. Dendrimer Based Nanomedicine. Hackensack, NJ: World Scientific Publishing, 2007.

Hong S, Leroueil PR, Janus EK, Peters JL, Kober MM, Islam MT, Orr BG, Baker JR, Banaszak Holl MM. Interaction of polycationic polymers with supported lipid bilayers and cells: Nanoscale hole formation and enhanced membrane permeability. Bioconjugate Chemistry 2006;17 (3):728-34. DOI

Hong S, Hessler JA, Banaszak Holl MM, Leroueil PR, Mecke A, Orr BG. Physical Interactions of Nanoparticles with Biological Membranes: The Observation of Nanoscale Hole Formation. Journal of Chemical Health & Safety 2006;13 (3):16-20. DOI

Hong S, Bielinska AU, Mecke A, Keszler B, Beals JL, Shi XY, Balogh L, Orr BG, Baker JR, Banaszak Holl MM. Interaction of poly(amidoamine) dendrimers with supported lipid bilayers and cells: Hole formation and the relation to transport. Bioconjugate Chemistry 2004;15 (4):774-82. DOI