Department of Biopharmaceutical Sciences

College of Pharmacy

Hyun-Young Jeong, Pharm.D., Ph.D.

Hyun-Young Jeong, Ph.D.

Assistant Professor of Pharmacokinetics

Contact Information
833 South Wood Street
117B Pharm
, MC 886
Chicago, IL 60612-7231
Office: (312) 996-7820
Fax: (312) 996-0379
Lab Website


Ph.D. - University of Illinois at Chicago - 2004
Pharm.D. - University of Illinois at Chicago - 2001

Research Interests

Altered pharmacokinetics in pregnancy
  (Related Publications)

  Clinical pharmacokinetics
(Related Publications)

Regulation of drug metabolizing enzymes
(Related Publications)

  Population pharmacokinetics

Drug metabolism
(Related Publications)

  Nuclear receptors
(Related Publications)

Molecular pharmacology
(Related Publications)


Koh KH, Pan 1, Zhang W, McLachlan 1, Urrutia R, Jeong HY. Kr├╝ppel-like factor 9 promotes hepatic cytochrome P450 2D6 expression during pregnancy in CYP2D6-humanized mice. Mol Pharmacol. 2014 Dec;86(6):727-35. PMID: 25217496

Chen H, Yang K, Choi S, Fischer JH, Jeong HY. Upregulation of UDP-glucuronosyltransferase (UGT) 1A4 by 17{beta}-Estradiol: a Potential Mechanism of Increased Lamotrigine Elimination in Pregnancy. Drug Metab Dispos. 2009 Jun 22. DOI

Choi S, Sainz B Jr, Corcoran P, Uprichard S, Jeong HY. Characterization of increased drug metabolism activity in dimethyl sulfoxide (DMSO)-treated Huh7 hepatoma cells. Xenobiotica. 2009 Mar;39(3):205-17. DOI

Shord SS, Cavallari LH, Gao W, Jeong HY, Deyo K, Patel SR, Camp JR, Labott SM, Molokie RE. The pharmacokinetics of codeine and its metabolites in Blacks with sickle cell disease. Eur J Clin Pharmacol. 2009 Jul;65(7):651-8. Epub 2009 Apr 9.

Jeong HY, Choi S, Song JW, Chen H, Fischer JH. Regulation of UDP-glucuronosyltransferase (UGT) 1A1 by progesterone and its impact on labetalol elimination. Xenobiotica. 2008 Jan;38(1):62-75. DOI

Jeong HY, Kaplan B. Therapeutic monitoring of mycophenolate mofetil. Clin J Am Soc Nephrol. 2007;2(1):184-91. DOI

Jeong HY, Chiou WL. Role of P-glycoprotein in the hepatic metabolism of tacrolimus. Xenobiotica. 2006 Jan;36(1):1-13.

Chiou WL, Ma C, Wu TC, Jeong HY. Unexpected lack of effect of the rifampin-induced P-glycoprotein on the oral bioavailability of its substrate, talinolol, in humans: implication in phenotyping. J Pharm Sci. 2003 Jan;92(1):4-7

Wu TC, Ma C, Jeong HY, Yao HM, Chiou WL. Comparison of gastrointestinal absorption between human and rat: the role of intestinal absorptive surface area and unstirred aqueous layer. Food Chem Toxicol. 2002 Nov;40(11):1727-8

Chiou WL, Wu TC, Ma C, Jeong HY. Enhanced oral bioavailability of docetaxel by coadministration of cyclosporine: quantitation and role of P-glycoprotein. J Clin Oncol. 2002 Apr 1;20(7):1951-2

Chiou WL, Jeong HY, Wu TC, Ma C.  Use of erythromycin breath test for in vivo assessments of cytochrome P4503A activity and dosage individualization. Clin Pharmacol Ther. 2001 Oct;70(4):305-10

Chiou WL, Jeong HY, Chung SM, Wu TC. Evaluation of using dog as an animal model to study the fraction o f oral dose absorbed of 43 drugs in humans. Pharm Res. 2000 Feb;17(2):135-40

Chiou WL, Ma C, Chung SM, Wu TC and Jeong HY. Similarity in the linear and nonlinear oral absorption of drugs between human and rat.  Int J Clin Pharmacol Ther. 2000 Nov;38(11):532-9