Department of Pharmacy Practice

College of Pharmacy
masthead

Gail B. Mahady

 Gail B. Mahady Gail B. Mahady, PhD
Associate Professor
Pharmacy Practice
Email mahady@uic.edu
Phone 312-996-1669
Fax 312-413-5894
Office 122 PHARM
US Mail 833 South Wood Street, RM164 MC886, Chicago, IL 60612

Research Interests
  1. Novel natural agents for treatment/prevention of infectious disease
    The screening of plant-based medicines for in vitro and in vivo activity against Helicobacter pylori and Chlamydia pneumonia. This project is partially funded by the NIH/NCCAM. The long-term objectives of this project are the discovery of plant-based antimicrobial drugs from medicinal and food plants for the prevention and treatment of Helicobacter pylori infections in humans. The proposal is based on the following hypothesis. Many medicinal and food plants are used around the world for the treatment of gastritis, dyspepsia and peptic ulcers, and some plant species also have experimental antibacterial activity, therefore these plant species are candidates for novel antibacterial agents against H. pylori infections.
  2. Center for Botanical Dietary Supplements Research on Women's Health
    The Center is one of the five Botanical Centers funded by the NCCAM/NIH/ODS focusing its efforts on the investigation of the clinical safety and efficacy of 10 herbal supplements widely used in the U.S. for the symptomatic treatment of menopause, premenstrual syndrome and chronic urinary tract infections. Additional studies will address mechanisms of action, identification of the active chemical constituents, and characterization of metabolism, bioavailability and pharmacokinetics of the active constituents. The multidisciplinary research team at UIC includes internationally renowned experts in the fields of pharmacognosy, medicinal chemistry, pharmacy practice, obstetrics and gynecology, geriatrics, surgical oncology, and mathematics and statistics.
  3. WHO Monographs on Selected Medinical Plants Volume IV
    A joint project between the World Health Organization's Traditional Medicines Programme and the WHO Collaborating Center at The University of Illinois. The monographs, currently Volumes I-III are extensive reviews of widely used medicinal plants from around the world. This project is currently funded by the WHO-TRM.
Education

1991 Ph.D., University of Illinois at Chicago in Pharmacognosy
1979 B.S. in Pharmaceutical Chemistry, Dalhousie University

Current UIC Appointments
2001 to present Assistant Professor, Department of Pharmacy Practice


Representative Publications
  1. Farnsworth, N.R., Fong, H.H.S. and Mahady, G.B. (2002) WHO Model Monographs on Selected Medicinal Plants. Vol II, World Health Organization, Traditional Medicine Programme, Geneva, Switzerland.
  2. Farnsworth, N.R., Fong, H.H.S. and Mahady, G.B. (1999) WHO Monographs of Selected Medicinal Plants. Vol. 1, World Health Organization, Traditional Medicine Programme, Geneva, Switzerland.
  3. J. Liu, J.E. Burdette, S. Deng, S.M. Schlecht, J.M. Pezzuto, J.L. Bolton, G.B. Mahady, and N.R. Farnsworth*. Estrogenic activity of Vitex agnus-castus and Linoleic Acid, Phytomedicine 2004, 10:213.
  4. Mahady GB, Pendland SL, Yun GS, Lu ZZ, Stoia A. Ginger (Zingiber officinale Roscoe) and the gingerols inhibit the growth of Cag A+ strains of Helicobacter pylori. Anticancer Res. 2003, 23(5A): 3699-3702.
  5. Schriever C, Mahady GB, Pendland S. Red wine, resveratrol, Chlamydia pneumonia and the French Connection. Atherosclerosis 2003, 171(2): 379-380.

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