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Drug Information Updates


University of Illinois at Chicago Medical Center Newsletter:

The RxPress

Overview of methamphetamine

Anabolic steroids - an overview

Corticosteroids and Head Trauma – Results from the CRASH trial

Update to the National Cholesterol Education Program (NCEP) Adult Treatment Panel III Guidelines 2004

Prevention of perinatal HIV transmission

Practice guidelines for outpatient parenteral antimicrobial therapy: a summary

Review of drug-disease interactions in heart failure

Enfuvirtide (Fuzeon®) – Consensus recommendations

SSRIs and risk of suicide in children and adolescents—Report of the Task Force on SSRIs and Suicidal Behavior in Youth

CDC updates guidelines for use of rifamycins and antiretroviral therapy

Over-the-counter analgesics/antipyretics – the Food and Drug Administration (FDA) consumer safety education campaign

Practice Guidelines for the Management of Community-Acquired Pneumonia in Adults – Update 2003

Selection of Antibiotic Therapy for Complicated Intra-abdominal Infections—2003 Guidelines

Drug-Eluting Stents and the Potential Risk of Thrombosis

COMET: The results and the controversy

Management of hypertension in the African American population – consensus statement summary

Smallpox: an overview

Primary prevention of hypertension. Clinical and public health advisory from the National High Blood Pressure Education Program.

Use of thrombolytics in the treatment of empyema

Cross sensitivity between penicillins and cephalosporins

Pleural effusions and Pleurodesis

West Nile Virus: An Update

Summary of U.S. Public Health Service guidelines for postexposure prophylaxis: HBV, HCV, HIV

Benzyl alcohol toxicity in neonates

Use of pain medications in hepatic insufficiency

Allergic Reactions to Local Anesthetics

Desensitization in a patient with a penicillin allergy

Risk of development of spinal/epidural hematoma with enoxaparin

Extravasation: a review

Health information on the Internet

HEALTH INFORMATION ON THE INTERNET

Use of the internet to obtain healthcare related information is a growing aspect of drug information. The Drug Information Center at the University of Illinois at Chicago routinely uses web sites to aid in retrieving information. Advantages of using internet sites include fast retrieval of information and the fact that the most current healthcare information is often posted on the internet before it is available in any published form. However, the quality of healthcare information on the World Wide Web may be suspect. Internet users should be aware of ways to evaluate the quality of a web site including:

  • Credentials of the authorship of the web page.
  • Availability of references for the clinical content provided. Information without references should receive low weight in clinical decision-making.
  • Disclosure of owner/sponsor of the web page.
  • Frequency of updates for the site.
  • Whether or not the site has an expert advisory board that evaluates content of the site.
  • Seal of approval from organizations that review health care sites (e.g. HONcode, Internet Healthcare Coalition, VIPPS, and Medical Matrix).
  • Web-site affiliation (commercial, educational, nonprofit, military, or governmental).

The following is a list of useful internet sites that may aid you in retrieving information relevant to your clinical practice. Many of these sites are free to use, will allow you to sign up for email notifications on important clinical information, and provide links to other healthcare related sites.

MD Consult www.mdconsult.com – Current version of over 30 major textbooks including Cecil’s Textbook of Internal Medicine. Subscription service - $200/year. Ten-day free trial.

Harrison’s Principals of Internal Medicine www.harrisononline.com – Textbook online. Subscription service - $89/year. Four-week free trial.

Merck Manual www.merck.com – Diagnosis and Therapy/Geriatrics. Both manuals are available online for free.

Emedicine www.emedicine.com – Free on-line textbooks for various medical and surgical specialty areas.

Agency for Healthcare Research and Quality www.ahcpr.gov – On-line clinical practice guidelines for disease states including heart failure, unstable angina, otitis media, pressure ulcer prevention, tobacco cessation, urinary incontinence, acute pain, etc.

American Academy of Pediatrics www.aap.org – The AAP site contains useful information on pediatric issues including news releases and guidelines. Examples of guidelines include circumcision, ADHD, urinary tract infections, Lyme disease, and vaccines.

American Pharmaceutical Association www.aphanet.org – Web site contains information on current drug shortages, abstracts of articles from JAPhA, and clinical pharmacy services.

American Thoracic Society www.thoracic.org – Contains statements and position papers in reference to microbiology, tuberculosis, and other pulmonary infections. Also contains information on adult and pediatric respiratory diseases.

American Society of Clinical Oncology www.asco.org – Contains ASCO guidelines for chemotherapy-related nausea and vomiting, role of bisphosphonates in breast cancer, etc. All downloadable in PDF format.

American Society of Health-System Pharmacists www.ashp.org. – Site contains Technical Assistance Bulletins, Practice Resource Areas, AHFS First Fax (updated monographs), ASHP therapeutic guidelines and position statements.

Infectious Diseases Society of America www.idsociety.org – Contains various infectious diseases guidelines in PDF format.

Institute for Safe Medication Practices www.ismp.org – Home of the ISMP Medication Safety Alert newsletter. Contains information on medication error reporting as well as a link to the recent Institute of Medicine report on medication errors.

American Medical Association www.ama-assn.org – Web site for the AMA. Contains information centers on HIV/AIDS, asthma, migraine, and women’s health. Links to JAMA on-line and Archives journals. Will soon be viewable only by subscription.

American Society of Parenteral and Enteral Nutritionists www.clinnutr.org -- Web site contains guidelines for use of parenteral and enteral nutrition in adult and pediatric patients and standards of practice.

American Society of Consultant Pharmacists www.ascp.com – Site of The Consultant Pharmacist journal – full-text. Also include guidelines related to long-term care including Psychotherapeutic Medications in Older Adults.

Center for Science in the Public Interest www.cspinet.com – Consumer-focused site. Educates the public about nutrition and alcohol issues.

Centers for Disease Control and Prevention www.cdc.gov – Site contains the on-line version of Morbidity and Mortality Weekly Report, Emerging Infectious Disease journal, information on traveler’s health, CDC prevention guidelines, and health-related hoaxes.

Centerwatch www.centerwatch.com – Listing of ongoing clinical trials by disease state, NIH studies, new FDA drug approvals, and a clinical trial notification service.

American College of Chest Physicians www.chesnet.org – Contains clinical information including evidence based practice guidelines, consensus statements, and patient education guides.

National Guideline Clearinghouse www.guideline.gov – Guidelines, guidelines, and more guidelines!!

National Institutes of Health www.nih.gov – Contains links to the following health-related institutes and centers:

  • National Cancer Institute
  • National Eye Institute
  • National Heart, Lung, and Blood Institute
  • National Human Genome Research Institute
  • National Institute on Aging
  • National Institute on Alcohol Abuse and Alcoholism
  • National Institute of Allergy and Infectious Diseases
  • National Institute of Arthritis and Musculoskeletal and Skin Diseases
  • National Institute of Child Health and Human Development
  • National Institute on Deafness and Other Communication Disorders
  • National Institute of Dental and Craniofacial Research
  • National Institute of Diabetes and Digestive and Kidney Diseases
  • National Institute on Drug Abuse
  • National Institute of Environmental Health Sciences
  • National Institute of General Medical Sciences
  • National Institute of Mental Health
  • National Institute of Neurological Disorders and Stroke
  • National Institute of Nursing Research
  • National Library of Medicine – Free Medline
  • Warren Grant Magnuson Clinical Center
  • National Center for Complementary and Alternative Medicine
  • Center for Scientific Research

Clinical Pharmacology Online cp.gsm.com – Now subscription-based on-line version. Contains drug information, patient monographs, drug interactions, adverse drug reactions, IV compatibility, and product identification components.

Clinical Trials www.clinicaltrials.gov – This site is a service of the National Institutes of Health and was developed by the National Library of Medicine. Contains current information about clinical research studies.

Food and Drug Administration www.fda.gov – Contains consumer drug information, information on the MedWatch reporting program, orphan drug news,the electronic orange book of therapeutic equivalence, drug shortages, and information on foods, human drugs, animal drugs, biologics, and cosmetics.

Quackwatch www.quackwatch.com – Web-based guide to health care fraud.

Pharmaceutical Research and Manufacturers of America www.phrma.org – Information on drugs in development and the drug development and approval process. Also contains the annual business reports for the pharmaceutical industry.

Oncolink www.oncolink.com – Web site produced by the University of Pennsylvania Cancer Center. Searchable site focused on cancer therapy.

Drugs that prolong the Q-T interval www.torsades.org – contains a list of drugs that prolong the Q-T interval and/or induce Torsades de Pointes. The list is frequently updated and contains comments as to the severity of the effect. Additionally, if the user clicks on "More Info", they are automatically brought to the results of a MEDLINE search regarding the drug in question with Q-T interval and Torsades de Pointes. The site is maintained by Georgetown University Medical Center.

Cardiosource www.cardiosource.com – Large cardiology-focused web site containing trial news, cardiology journals (view abstracts for free), and links to the American College of Cardiology/American Heart Association guidelines. Registration is free.

The Heart www.theheart.org - Additional cardiology-focused web site with daily news, journals, cybersessions, etc.

United States Pharmacopoeia www.usp.org – Contains information on dietary supplements, veterinary medicine, and basic drug information.

Natural Database www.naturaldatabase.com – On-line version of Natural Medicines Comprehensive Database. Contains monographs on a variety of herbal products. Cost: $92/year for web version.

Joint Commission on Accreditation of Healthcare Organizations www.jcaho.org -Home page of JCAHO. Contains information on standards for various practice settings.

Latex Allergy www.njha.com/html/latex.html - Site developed by the New Jersey Hospital Association. Extensive listings of products containing latex.

Micromedex www.micromedex.com – Home page of the Micromedex system. Does contain daily news updates and information on how to subscribe to the system.

Doctor’s Guide www.docguide.com – Web site contains daily health news updates, new drugs/indications, webcasts, cases, and health channels. Free registration for your own personal edition.

RxAssist www.rxassist.org – Web site dedicated to aiding health care professionals and their patients access pharmaceutical patient assistance programs.

HIVInsite kali.ucsf.edu – Site covering all aspects of HIV/AIDS including medical journals, journal club, journal scan, various guidelines, and the AIDS Knowledge Base.

AIDS Treatment Information Service www.hivatis.org – Site of the living documents for current treatment guidelines related to HIV/AIDS including treatment of HIV-infected adults and adolescents, pediatric HIV infection, perinatal infection, healthcare worker exposure guidelines, nonoccupational exposure, opportunistic infection guidelines, and tuberculosis guidelines.

Medscape www.medscape.com – Vast website covering an array of medical and pharmaceutical information. Free registration. May sign up to have certain information emailed directly to the individual on a regular basis.

MedMatrix www.medmatrix.org – Index of medical sites that is peer-reviewed by physicians. Contains an extensive list of medical "hypertextbooks". Free registration.

Dr. Koop www.drkoop.com – General medical information web site with extensive health-care related data.

Intelihealth www.intelihealth.com – General health database with featured health areas. Drug search capability. On-line medical dictionary.

HealthAnswers www.healthanswers.com – Information on a variety of health topics, diseases, and healthy lifestyles.

DynaMed www.dynamicmedical.com – Very general information on diseases from A to Z. Includes treatment, diagnosis, risks, description, and etiology. Free registration.

Free Medical Journals www.freemedicaljournals.com - Web site contains access to many free medical journals available throughout the internet.

New England Journal of Medicine www.nejm.org – Available on the internet to subscribers. The site does post early release full-text articles for free download.

FD&C Reports www.fdcreports.com – On-line version of Pink, Gold, Tan, Gray, and various other sheets. Contains summaries of the information contained within the present publication.

Multimedia Healthcare/Freedom LLC www.mmhc.com – Home site of the following full-text journals: Annals of Long-Term Care, Clinical Geriatrics, HHC Consultant, Journal of Gender-Specific Medicine, and MD net guide.

Pharmacist’s Letter www.pharmacistsletter.com – On-line version of Pharmacist’s Letter. Available to all subscribers via personal login and ID.

Medical Letter www.medicalletter.com – On-line version of Medical Letter. Available to all subscribers via personal login and ID.

WebMedLit www.webmedlit.com – Site scans the literature daily. Full text available for articles from numerous journals.

PNN Pharmacotherapy Line www.pharminfo.com/pubs/pnn/pnnordr.html – Summaries of latest medical information obtained via daily fax or email. Subscription only.

US Pharmacist www.uspharmacist.com – On-line site of US Pharmacist journal.

Drug Topics www.drugtopics.com – On-line home of Drug Topics journal.

Pharmacy Times www.pharmacytimes.com – Site contains online CE, an internet column, and an extensive compounding section.

Prevline www.health.org – National clearinghouse for alcohol and drug abuse information.

Beyond this list, all the major pharmaceutical companies have web sites, which may contain full prescribing information as well as patient information for their marketed medications. The specific web address for most pharmaceutical companies may be found within Facts and Comparisons. In addition, specific medications may have their own web site as well (e.g. http://www.zocor.com/simvastatin/zocor/consumer/index.jsp.) On-line pharmacies such as www.planetRx.com, www.drugstore.com, and www.virtualdrugstore.com may also be useful to find information on over-the-counter or natural products. Plus, search engines such as go.com, altavista.com, metacrawler.com, and dogpile.com aid individuals in sifting through the vast amount of healthcare related information that is available on the World Wide Web.

 

 

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